Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19638551.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/10/25
Hold-until Date:: 2025/05/03

AID:: 1963855

Select item 19635402.

ABL1 Biochemical Kinase Assay from US Patent US20240101536: "COMPOUNDS FOR TREATING CERTAIN LEUKEMIAS"

Source:: BindingDB

Protein Targets:: Tyrosine-protein kinase ABL1; ...
Total:: 1

Assay data:217 Active, 190 Activity ≤ 1 nM, 217 Activity ≤ 1 µM, 217 Tested

AID:: 1963540

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19633173.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/05/07
Modify Date:: 2024/05/13
Hold-until Date:: 2025/05/03

AID:: 1963317

Select item 19633164.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/05/07
Modify Date:: 2024/05/13
Hold-until Date:: 2025/05/03

AID:: 1963316

Select item 19633155.

Source:: National Center for Advancing Translational Sciences (NCATS)

Deposit Date:: 2024/05/07
Modify Date:: 2024/10/23
Hold-until Date:: 2025/05/03

AID:: 1963315

Select item 19628856.

ABL1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962885

Summary Related BioAssays by Target

Select item 19627817.

ABL1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962781

Summary Related BioAssays by Target

Select item 19626788.

ABL1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962678

Summary Related BioAssays by Target

Select item 19625799.

ABL1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962579

Summary Related BioAssays by Target

Select item 196240010.

ABL1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962400

Summary Related BioAssays by Target

Select item 196225311.

ABL1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1962253

Summary Related BioAssays by Target

Select item 196086512.

Inhibition of ABL1 (unknown origin) at 10 uM by biochemical hotspot kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1960865

Summary PubMed Citation Related BioAssays by Target

Select item 195884013.

Binding affinity to Abl-T315I mutant (unknown origin) assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:22 Active, 20 Activity ≤ 1 µM, 23 Tested

AID:: 1958840

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 195883914.

Binding affinity to Abl (unknown origin) assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:25 Active, 5 Activity ≤ 1 nM, 25 Activity ≤ 1 µM, 25 Tested

AID:: 1958839

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 195835415.

Inhibition of Abl (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:3 Tested

AID:: 1958354

Summary PubMed Citation Related BioAssays by Target

Select item 195646316.

Inhibition of His-tagged human recombinant ABL1 expressed in insect cells at 200 nM by Z'-lyte assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1956463

Summary PubMed Citation Related BioAssays by Target

Select item 195592917.

Inhibition of ABL (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:1 Tested

AID:: 1955929

Summary PubMed Citation Related BioAssays by Target

Select item 195591518.

Inhibition of ABL2 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL2

Assay data:1 Tested

AID:: 1955915

Summary PubMed Citation Related BioAssays by Target

Select item 195362619.

Inhibition of ABL (unknown origin) at 10 uM using magnesium acetate as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting based hotspot kinase assay relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase ABL1

Assay data:4 Tested

AID:: 1953626

Summary PubMed Citation Related BioAssays by Target

Select item 195009220.

Inhibition of BCR-ABL phospho-activation in human LAMA-84 cells at 100 nM incubated for 24 hrs by Western blot analysis

Source:: ChEMBL

Protein Targets:: Breakpoint cluster region protein; ...
Total:: 2

Assay data:1 Tested

AID:: 1950092

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (15)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (942)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (180)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (677)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (919)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (2)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
On Hold (4)
On hold BioAssays

Assay Project (10)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (2,454)
BioAssays extracted from the literature
NIH MLP (14)
BioAssays deposited by the NIH Molecular Libraries Program
Other (1,165)
BioAssays deposited by other experimentalists

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (3633)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1792584)
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PubChem BioAssay
LOC127897061 [Homo sapiens]
LOC127897061 [Homo sapiens]
Gene ID:127897061

Gene
PREDICTED: Bombus terrestris bifunctional heparan sulfate N-deacetylase/N-sulfot...
PREDICTED: Bombus terrestris bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (LOC100643169), transcript variant X2, mRNA
gi|2245552704|ref|XM_048409529.1|

Nucleotide
JGI_CABA3188.fwd NIH_XGC_tropKid1 Xenopus tropicalis cDNA clone IMAGE:7748023 5'...
JGI_CABA3188.fwd NIH_XGC_tropKid1 Xenopus tropicalis cDNA clone IMAGE:7748023 5', mRNA sequence
gi|59252539|gnl|dbEST|27758399|gb|D 69.1|

Nucleotide

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