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SPR Biosensor Assay from Article 10.1021/jm801475n: "A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy."
Assay data:1 Active, 6 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to Burkholderia pseudomallei IspF by STD NMR analysis
Assay data:1 Active, 2 Tested
Binding affinity to Escherichia coli IspF assessed as change in entropy at pH 7.4 measured by isothermal titration calorimetry method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to Escherichia coli IspF assessed as change in enthalpy at pH 7.4 measured by isothermal titration calorimetry method
Binding affinity to Escherichia coli IspF assessed as change in free energy at pH 7.4 measured by isothermal titration calorimetry method
Binding affinity to Escherichia coli IspF at pH 7.4 measured by isothermal titration calorimetry method
Ratio of apparent Kd for Burkholderia pseudomallei IspF at pH 6 to apparent Kd for Burkholderia pseudomallei IspF at pH 7.4
Binding affinity to Burkholderia pseudomallei IspF assessed as change in entropy at pH 8 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF assessed as change in entropy at pH 6 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF assessed as change in entropy at pH 7.4 measured by isothermal titration calorimetry method
Assay data:2 Tested
Binding affinity to Burkholderia pseudomallei IspF assessed as change in enthalpy at pH 8 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF assessed as change in enthalpy at pH 6 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF assessed as change in enthalpy at pH 7.4 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF assessed as change in free energy at pH 8 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF assessed as change in free energy at pH 6 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF assessed as change in free energy at pH 7.4 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF at pH 8 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF at pH 6 measured by isothermal titration calorimetry method
Binding affinity to Burkholderia pseudomallei IspF at pH 7.4 measured by isothermal titration calorimetry method
Assay data:4 Tested
Inhibition of Burkholderia pseudomallei IspF assessed as inhibition of CMP production using CDP-ME2P as substrate at 120 uM measured by HPLC method
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