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Primary qHTS assay for inhibitors of Glutamate pyruvate transaminase 2 (GPT2)
Assay data:249 Active, 449 Activity ≤ 1 µM, 100803 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Confirmatory qHTS assay for inhibitors of Glutamate pyruvate transaminase 2 (GPT2)
Assay data:90 Active, 3 Activity ≤ 1 µM, 93 Tested
Effect on GPT in rat hepatocytes relative to control
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Effect on glutamic pyruvate transaminase activity at 3 mg/ml
Assay data:1 Tested
Effect on glutamic pyruvate transaminase activity at 1 mg/ml
Effect on glutamic pyruvate transaminase activity at 0.1 mg/ml
Hepatoprotective activity against glutamate pyruvate transaminase (GTP) for thioacetamide-induced toxicity in rats at 6 mg/kg dose for 7 days by ip administration
Assay data:6 Tested
SummaryRelated BioAssays by Target
Effect of thioethanol on alanine aminotransferase inhibition by the compound at 10E-5
Assay data:2 Tested
Effect of glutathione on alanine aminotransferase inhibition by the compound at 10E-5
Effect of cysteine on alanine aminotransferase inhibition by the compound at 10E-5
Inhibitory activity against alanine aminotransferase was measured
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Concentration for complete inactivation of alanine aminotransferase
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