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Binding affinity to recombinant human CBX6 by microarray based assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of CBX6 (unknown origin) assessed as inhibition of CBX4 disruption by competitive FP assay
Assay data:2 Active, 4 Tested
Binding affinity to CBX6 (unknown origin) assessed as dissociation constant by fluorescence polarization analysis
Assay data:8 Active, 7 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to human N-terminal his-tagged CBX6 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pLysS by ITC method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to 15N-labeled CBX6ChD (8 to 65 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells at 200 uM by 1H-15N HSQC NMR spectroscopy
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to N-terminal His6-tagged human CBX6 (8 to 65 residues) expressed in Escherichia coli BL21 by surface plasmon resonance assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity to N-terminal His6-tagged human CBX6 (8 to 65 residues) expressed in Escherichia coli BL21 using FITC-peptide-3 as competitive binding probe by fluorescence polarization assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
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