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Binding affinity to MCM2 in human NCI-H1975 cells at 5 uM by pull down/LC-MS/MS analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Mcm2 in mouse C2C12 cells assessed as reduction in phospho-sites occupancy at 4 uM after 5 hrs by SILAC based LC-MS/MS analysis relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Induction of ubiquitination of FLAG-tagged MCM2 Q341A mutant (unknown origin) expressed in human 293T cells incubated for 4 hrs by magnetic beads technique based immunoblot analysis
Induction of ubiquitination of FLAG-tagged MCM2 in human 293T cells incubated for 4 hrs by magnetic beads technique based immunoblot analysis
Induction of ubiquitination of FLAG-tagged MCM2 Q341A mutant (unknown origin) expressed in human NCI-H1975 cells incubated for 24 hrs by magnetic beads technique based immunoblot analysis
Assay data:1 Tested
Induction of ubiquitination of FLAG-tagged MCM2 in human NCI-H1975 cells incubated for 24 hrs by magnetic beads technique based immunoblot analysis
Induction of ubiquitination of MCM2 in human NCI-H1975 cells incubated for 24 hrs by magnetic beads technique based immunoblot analysis
Induction of ubiquitination of MCM2 in human NCI-H1975 cells in presence of MLN4924 incubated for 24 hrs followed by MLN4924 addition and measured after 6 hrs by immunoblot analysis
Binding affinity to MCM2 in human NCI-H1975 cells assessed as reduction in MCM2 level measured up to 9 hrs by immunoblot analysis
Induction of ubiquitination of MCM2 in human NCI-H1975 cells at 140 nM in presence of MG132 incubated for 48 hrs followed by MG132 addition and measured after 12 hrs by immunoblot analysis
Induction of ubiquitination of MCM2 in human NCI-H1975 cells in presence of MG132 incubated for 48 hrs followed by MG132 addition and measured after 12 hrs by immunoblot analysis (Rvb = 1.4 No_unit)
Induction of ubiquitination of MCM2 in human NCI-H1975 cells incubated for 72 hrs by immunoblot analysis (Rvb = 1 No_unit)
Induction of ubiquitination of MCM2 in human NCI-H1975 cells incubated for 48 hrs by immunoblot analysis (Rvb = 1 No_unit)
Induction of ubiquitination of MCM2 in human NCI-H1975 cells incubated for 24 hrs by immunoblot analysis (Rvb = 1 No_unit)
Induction of ubiquitination of MCM2 in human PC9 cells incubated for 24 hrs by immunoblot analysis
Induction of ubiquitination of MCM2 in human H3255 cells incubated for 24 hrs by immunoblot analysis
Induction of ubiquitination of MCM2 in human NCI-H1975 cells incubated for 24 hrs by immunoblot analysis
Inhibition of Mcm2 phosphorylation at ser40/41 in S-phase of NHDF after 2 to 12 hrs
Inhibition of Mcm2 phosphorylation at serine139 in human A2780 cells at 1.2 to 20 uM after 24 hrs
Inhibition of Mcm2 phosphorylation at serine13 in human A2780 cells at 1.2 to 20 uM after 24 hrs
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