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Inhibition of SPOP signalling in human OS-RC2 cells assessed as accumulation of PTEN at 5 to 15 uM incubated for 12 hrs by Western blot analysis
Assay data:4 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of SPOP signalling in human OS-RC2 cells assessed as effect of DUSP7 mRNA expression at 1 to 10 uM incubated for 12 hrs by qRT-PCR analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of SPOP signalling in human OS-RC2 cells assessed as effect of PTEN mRNA expression at 1 to 10 uM incubated for 12 hrs by qRT-PCR analysis
Inhibition of SPOP signalling in human A498 cells assessed as effect of DUSP7 mRNA expression at 5 to 15 uM incubated for 12 hrs by qRT-PCR analysis
Assay data:1 Active, 1 Tested
Inhibition of SPOP signalling in human A498 cells assessed as effect of PTEN mRNA expression at 5 to 15 uM incubated for 12 hrs by qRT-PCR analysis
Inhibition of SPOP signalling in human OS-RC2 cells assessed as effect on total ERK level at 0.5 to 15 uM incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human OS-RC2 cells assessed as effect on total AKT level at 0.5 to 15 uM incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human A498 cells assessed as effect on total ERK level at 0.5 to 10 uM incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human A498 cells assessed as effect on total AKT level at 0.5 to 10 uM incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human OS-RC2 cells assessed as reduction in ERK phosphorylation at 0.5 to 15 uM incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human OS-RC2 cells assessed as reduction in AKT phosphorylation at 0.5 to 15 uM incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human A498 cells assessed as reduction in ERK phosphorylation at 0.5 to 10 uM incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human A498 cells assessed as reduction in AKT phosphorylation at 0.5 to 10 uM incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human OS-RC2 cells assessed as accumulation of PTEN incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human A498 cells assessed as accumulation of DUSP7 incubated for 12 hrs by Western blot analysis
Inhibition of SPOP signalling in human A498 cells assessed as accumulation of PTEN incubated for 12 hrs by Western blot analysis
Inhibition of SPOP/PTEN interaction in human HEK293T cells assessed as reduction in PTEN level incubated for 8 hrs by Western blot analysis
Inhibition of SPOP/PTEN interaction in human HEK293T cells assessed as reduction in SPOP level incubated for 20 mins by co-immunoprecipitation based Western blot analysis
Inhibition of SPOP/PTEN interaction in human OS-RC2 cells assessed as increase in SPOP level at 1 to 50 uM incubated for 20 mins by DARTS based Western blot analysis
Inhibition of SPOP/PTEN interaction in human A498 cells assessed as increase in SPOP level at 1 to 50 uM incubated for 20 mins by DARTS based Western blot analysis
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