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Inhibition of Ubc13/Uev1A interaction (unknown origin)
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Ubc13 (unknown origin) at 2.5 to 10 uM preincubated for 20 mins followed by E1, Ub and ATP addition measured after 40 mins iby Western blot analysis
Assay data:1 Active, 6 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Ratio of leucettamol A IC50 to compound IC50 for recombinant human Ubc13-Uev1A interaction expressed in Escherichia BL21
Assay data:1 Tested
Inhibition of recombinant human Ubc13-Uev1A interaction expressed in Escherichia BL21 after 1.5 hrs by ELISA
Assay data:2 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
SAR analysis of small molecule UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay - Set 4
Assay data:34 Active, 3 Activity ≤ 1 µM, 78 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
SAR analysis of small molecule UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay - Set 3
Assay data:1 Active, 19 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
SAR analysis of small molecule UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay - Set 2
Assay data:9 Active, 2 Activity ≤ 1 µM, 27 Tested
SAR analysis of small molecule UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
Assay data:104 Active, 10 Activity ≤ 1 µM, 129 Tested
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
Assay data:296 Active, 11 Activity ≤ 1 µM, 353 Tested
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
Assay data:354 Active, 5 Activity ≤ 1 µM, 1210 Tested
Single concentration confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
Assay data:970 Active, 1430 Tested
SAR Analysis of interference of small molecule inhibitors of SUMOylation in an AlphaScreen assay
Assay data:5 Active, 38 Tested
SAR analysis of small molecule inhibitors of SUMOylation in an AlphaScreen assay in the presence of BSA
Assay data:67 Active, 5 Activity ≤ 1 µM, 88 Tested
SAR analysis of small molecule inhibitors of SUMOylation in an AlphaScreen assay
Assay data:69 Active, 8 Activity ≤ 1 µM, 81 Tested
SAR analysis of Ubc13-Ubiquitination selectivity in a TR-FRET assay for In Vitro dose response studies - set 2
Assay data:38 Active, 17 Activity ≤ 1 µM, 88 Tested
Summary of small molecule inhibitors of UBC13 Polyubiquitin
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay
Assay data:1540 Active, 330481 Tested
Inhibition of Ubc13-MMS2 interaction by ELISA
Inhibition of human Ubc13-Uev1A interaction expressed in Escherichia BL21 after 15 mins by ELISA
Assay data:3 Tested
SAR analysis of Ubc13-Ubiquitination selectivity in a TR-FRET assay for In Vitro dose response studies
Assay data:30 Active, 114 Tested
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