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Purinergic P2Y Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Antagonist activity at rat P2Y4 transfected in xenopus oocyte cell
Assay data:1 Active, 1 Tested
Antagonist activity at rat P2Y4
Antagonist activity at human P2Y4
Agonist activity at human P2Y4 transfected in human 1321N1 cells at 100 uM relative to control
Agonist activity at rat P2Y4 transfected in human 1321N1 cells at 100 uM relative to control
Agonist activity at human P2Y4 transfected in human 1321N1 cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Antagonist activity at human P2Y4R expressed in human 1321N1 cells assessed as inhibition of UDP-induced calcium mobilization at 100 uM by FLIPR assay relative to control
Assay data:5 Tested
Antagonist activity at P2Y4R (unknown origin) expressed in human 1321N1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 15 mins in presence of IBMX by chromatography
SummaryPubMed CitationRelated BioAssays by Target
Antagonist activity at human P2Y4R expressed in HEK293 cells assessed as inhibition of UTP-induced IP3 production preincubated for 0.5 hrs followed by UTP stimulation by ELISA
Purinergic P2Y Eurofins-Panlabs radioligand binding assay
Assay data:4 Tested
Assay data:9 Tested
PRESTO-Tango GPCRome screening (P2RY4)
P2Y CEREP ligand profiling
P2Y-purinergic receptor CEREP ligand profiling
P2Y Ligand binding assay
Antagonist activity at human P2Y4 receptor expressed in human 1321N1 cells assessed as inhibition of UTP-induced intracellular calcium influx at 10 to 100 uM preincubated for 20 mins followed by UTP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay
Assay data:36 Tested
Antagonist activity against human P2Y4 in human 1321N1 cells assessed as effect on calcium transients
Agonist activity at human P2Y4 in human 1321N1 cells assessed as effect on calcium transients
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