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Thiol reactivity of compound measured by TNB2- assay
Assay data:19 Active, 49 Tested
SummaryCompounds, ActivePubMed Citation
Thiol reactivity of compound at 100 uM measured by DTNB assay
Assay data:1 Active, 49 Tested
Redox activity of compound assessed as redox index at 1 uM measured by resazurin assay
Assay data:49 Tested
SummaryPubMed Citation
Redox activity of compound assessed as redox index at 10 uM measured by resazurin assay
Redox activity of compound assessed as redox index at 100 uM in presence of 100 uM TCEP measured by H2DCFDA assay
Redox activity of compound assessed as redox index at 100 uM measured by H2DCFDA assay
Redox activity of compound assessed as redox index at 100 uM in presence of 1 mM DTT measured by HRP-PR assay
Redox activity of compound assessed as redox index at 100 uM measured by HRP-PR assay
Aqueous stability of the compound at pH 7.4 measured after 60 mins by spectrophotometric analysis
Assay data:34 Active, 37 Tested
Inhibition of recombinant Escherichia coli DdlB assessed as residual activity at 500 uM using D-alanine as substrate incubated for 20 mins and measured by malachite green based colorimetric assay relative to control
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Mycobacterium tuberculosis MetAP1a assessed as residual activity at 625 uM using L-methionine 7-amido-4-methylcoumarin as fluorogenic substrate and measured by fluorescence based assay
Inhibition of recombinant SARS-CoV-2 3CLpro expressed in Escherichia coli NiCo21(DE3) assessed as residual activity at 500 uM using DABCYL-KTSAVLQSGFRKME-EDANS as substrate preincubated for 30 mins in presence of 1mM DTT followed by substrate addition and measured by FRET assay relative to control
Inhibition of recombinant SARS-CoV-2 3CLpro expressed in Escherichia coli NiCo21(DE3) assessed as residual activity at 500 uM using DABCYL-KTSAVLQSGFRKME-EDANS as substrate preincubated for 30 mins followed by substrate addition and measured by FRET assay relative to control
Inhibition of recombinant Escherichia coli MurA assessed using UDP-N-acetylglucosamine as substrate preincubated for 30 mins in presence of 1 mM DTT followed by substrate addition and measured by malachite green based colorimetric assay
Assay data:14 Tested
Inhibition of recombinant Escherichia coli MurA assessed as residual activity at 500 uM using UDP-N-acetylglucosamine as substrate preincubated for 30 mins in presence of 1 mM DTT followed by substrate addition and measured by malachite green based colorimetric assay relative to control
Inhibition of recombinant Escherichia coli MurA assessed as residual activity at 500 uM using UDP-N-acetylglucosamine as substrate and measured by malachite green based colorimetric assay relative to control
Inhibition of recombinant Escherichia coli MurA assessed as residual activity at 500 uM using UDP-N-acetylglucosamine as substrate preincubated for 30 mins followed by substrate addition and measured by malachite green based colorimetric assay relative to control
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