Related BioAssays, by Same Project (List) for PubChem BioAssay (Select - PubChem BioAssay - NCBI

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Items: 14

Select item 5048781.

Inhibitors of USP1/UAF1: Summary

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP1 protein, partial

AID:: 504878

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 7432552.

Inhibitors of USP1/UAF1: Primary Screen

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP1 protein, partial

Assay data:906 Active, 1 Activity ≤ 1 nM, 3174 Activity ≤ 1 µM, 392718 Tested

AID:: 743255

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 6516263.

Inhibitors of USP1/UAF1: SAR in USP2 diubiquitin SDS-PAGE gel assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP2 protein

Assay data:1 Tested

AID:: 651626

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 6516254.

Inhibitors of USP1/UAF1: SAR in USP5 diubiquitin SDS-PAGE gel assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP5 protein

Assay data:1 Tested

AID:: 651625

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 6516245.

Inhibitors of USP1/UAF1: SAR in USP7 diubiquitin SDS-PAGE gel assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: ubiquitin carboxyl-terminal hydrolase 7 isoform 1

Assay data:1 Tested

AID:: 651624

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 6516236.

Inhibitors of USP1/UAF1: SAR in USP8 diubiquitin SDS-PAGE gel assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP8 protein, partial

Assay data:1 Tested

AID:: 651623

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 6516227.

Inhibitors of USP1/UAF1: SAR in USP46/UAF1 diubiquitin SDS-PAGE gel assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: ubiquitin specific protease 46

Assay data:1 Tested

AID:: 651622

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 6516218.

Inhibitors of USP1/UAF1: SAR in USP1/UAF1 diubiquitin SDS-PAGE gel assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP1 protein, partial

Assay data:1 Active, 1 Tested

AID:: 651621

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 6516059.

Inhibitors of USP1/UAF1: SAR in Primary Assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP1 protein, partial

Assay data:109 Active, 70 Activity ≤ 1 µM, 147 Tested

AID:: 651605

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 62434610.

Inhibitors of USP1/UAF1: Hit Validation in USP1 Diubiquiting Gel Assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP1 protein, partial

Assay data:19 Active, 25 Tested

AID:: 624346

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 62434511.

Inhibitors of USP1/UAF1: Hit Validation in USP2 Diubiquiting Gel Assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP2 protein

Assay data:3 Tested

AID:: 624345

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 62434112.

Inhibitors of USP1/UAF1: Hit Validation in USP7 Diubiquiting Gel Assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: ubiquitin carboxyl-terminal hydrolase 7 isoform 1

Assay data:3 Active, 3 Tested

AID:: 624341

Summary Compounds, Active PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 54032713.

Inhibitors of USP1/UAF1: Hit Validation in Primary Assay

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP1 protein, partial

Assay data:25 Active, 1 Activity ≤ 1 µM, 50 Tested

AID:: 540327

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 50486514.

Inhibitors of USP1/UAF1: Pilot qHTS

Source:: National Center for Advancing Translational Sciences (NCATS)

Protein Target:: USP1 protein, partial

Assay data:358 Active, 21 Activity ≤ 1 µM, 8590 Tested

AID:: 504865

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

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Target

Proteins (14)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (7)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (4)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (4)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Assay Project (14)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

NIH MLP (14)
BioAssays deposited by the NIH Molecular Libraries Program

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Related BioAssays, by Same Project (List) for PubChem BioAssay (S... (14)
Related BioAssays, by Same Project (List) for PubChem BioAssay (Select 743255)
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Mixture/Component Compounds for PubChem Compound (Select 15710031... (1)
Mixture/Component Compounds for PubChem Compound (Select 157100317)
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