Related BioAssays, by Gene Interaction (List) for PubChem BioAssay (Se - PubChem BioAssay - NCBI

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Select item 19624461.

RPS6KA3 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Ribosomal protein S6 kinase alpha-3

Assay data:1 Tested

AID:: 1962446

Summary Related BioAssays by Target

Select item 19622992.

RPS6KA3 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Ribosomal protein S6 kinase alpha-3

Assay data:1 Tested

AID:: 1962299

Summary Related BioAssays by Target

Select item 19566273.

Displacement of [11C]PBB3 in human brain tau incubated for 30 mins by radioligand binding assay relative to control

Source:: ChEMBL

Protein Target:: Microtubule-associated protein tau

Assay data:22 Tested

AID:: 1956627

Summary PubMed Citation Related BioAssays by Target

Select item 19566264.

Displacement of [11C]PBB3 in human brain tau incubated for 30 mins by radioligand binding assay

Source:: ChEMBL

Protein Target:: Microtubule-associated protein tau

Assay data:18 Active, 1 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 22 Tested

AID:: 1956626

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19564875.

Inhibition of MEK3 (unknown origin) by discoverX kinomescan assay

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 3

Assay data:1 Tested

AID:: 1956487

Summary PubMed Citation Related BioAssays by Target

Select item 19564806.

Inhibition of MEK3 (unknown origin)

Source:: ChEMBL

Protein Target:: Dual specificity mitogen-activated protein kinase kinase 3

Assay data:3 Tested

AID:: 1956480

Summary PubMed Citation Related BioAssays by Target

Select item 19540367.

Binding affinity to insulin regulated aminopeptidase (unknown origin)

Source:: ChEMBL

Protein Target:: Leucyl-cystinyl aminopeptidase

Assay data:10 Active, 7 Activity ≤ 1 µM, 11 Tested

AID:: 1954036

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19531858.

Inhibition of recombinant human C-terminally-His tagged NAMPT incubated for 2 to 3 hrs by TR-FRET assay

Source:: ChEMBL

Protein Target:: Nicotinamide phosphoribosyltransferase

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1953185

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19498199.

Inhibition of RSK2 (unknown origin)

Source:: ChEMBL

Protein Target:: Ribosomal protein S6 kinase alpha-3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1949819

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194832710.

Inhibition of tau 4R1N phosphorylation (unknown origin) at S396 residue transfected in human U2OS cells coexpressing GFP-tagged beta catenin incubated overnight by high content imaging assay

Source:: ChEMBL

Protein Target:: Microtubule-associated protein tau

Assay data:12 Active, 12 Activity ≤ 1 µM, 12 Tested

AID:: 1948327

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194784711.

Inhibition of N-terminal GST-tagged human recombinant G9a (785 to 1210 residues) expressed in baculovirus infected Sf9 cells incubated for 1 hr by AlphaLISA analysis

Source:: ChEMBL

Protein Target:: Histone-lysine N-methyltransferase EHMT2

Assay data:45 Active, 20 Activity ≤ 1 µM, 57 Tested

AID:: 1947847

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194784512.

Inhibition of G9a (unknown origin)

Source:: ChEMBL

Protein Target:: Histone-lysine N-methyltransferase EHMT2

Assay data:7 Active, 6 Activity ≤ 1 µM, 7 Tested

AID:: 1947845

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 194746813.

Inhibition of USP14 (unknown origin) using ubiquitin rhodamine 110 as substrate in presence of Proteasome-VS at Kd at 1 to 10 uM by DUBprofiler fluorometric assay

Source:: ChEMBL

Protein Target:: Ubiquitin carboxyl-terminal hydrolase 14

Assay data:2 Tested

AID:: 1947468

Summary PubMed Citation Related BioAssays by Target

Select item 193845114.

Inhibition of G9a (unknown origin)

Source:: ChEMBL

Protein Target:: Histone-lysine N-methyltransferase EHMT2

Assay data:2 Active, 2 Tested

AID:: 1938451

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193843115.

Inhibition of G9a (unknown origin)

Source:: ChEMBL

Protein Target:: Histone-lysine N-methyltransferase EHMT2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1938431

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193760416.

Inhibition of tau phosphorylation (unknown origin)

Source:: ChEMBL

Protein Target:: Microtubule-associated protein tau

Assay data:68 Active, 1 Activity ≤ 1 nM, 60 Activity ≤ 1 µM, 68 Tested

AID:: 1937604

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 193586217.

Inhibition of recombinant human IDE using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate at 0.4 uM measured after 45 mins by fluorescence assay relative to control

Source:: ChEMBL

Protein Target:: Insulin-degrading enzyme

Assay data:1 Tested

AID:: 1935862

Summary PubMed Citation Related BioAssays by Target

Select item 193586118.

Inhibition of recombinant human IDE using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate measured after 45 mins by fluorescence assay

Source:: ChEMBL

Protein Target:: Insulin-degrading enzyme

Assay data:1 Active, 5 Tested

AID:: 1935861

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 193462919.

Induction of degradation NAMPT (unknown origin) assessed as maximum degradation relative to control

Source:: ChEMBL

Protein Target:: Nicotinamide phosphoribosyltransferase

Assay data:1 Tested

AID:: 1934629

Summary PubMed Citation Related BioAssays by Target

Select item 193462820.

Induction of degradation NAMPT (unknown origin)

Source:: ChEMBL

Protein Target:: Nicotinamide phosphoribosyltransferase

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1934628

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (65)
BioAssays with protein sequences specified as targets

BioActivity

Chemical Probes (1)
BioAssays with compounds reported as validated chemical probes

Active Compounds (778)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (49)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (411)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Summary (5)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (661)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (52)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (1,555)
BioAssays extracted from the literature
NIH MLP (58)
BioAssays deposited by the NIH Molecular Libraries Program
Other (92)
BioAssays deposited by other experimentalists

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Related BioAssays, by Gene Interaction (List) for PubChem BioAssa... (1705)
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PubChem BioAssay
RecName: Full=Protein adenylyltransferase FICD; AltName: Full=AMPylator FICD; Al...
RecName: Full=Protein adenylyltransferase FICD; AltName: Full=AMPylator FICD; AltName: Full=De-AMPylase FICD; AltName: Full=FIC domain-containing protein
gi|81873906|sp|Q8BIX9.1|FICD_MOUSE

Protein
Physcomitrium patens
Physcomitrium patens
Reference Sequence project

BioProject
BioProject Links for Nucleotide (Select 1373984064) (1)
BioProject
Solea senegalensis isolate Sse05_10M linkage group LG5, whole genome shotgun seq...
Solea senegalensis isolate Sse05_10M linkage group LG5, whole genome shotgun sequence
gi|2064975774|gb|JAGKHQ010000017.1| WGS:JAGKHQ01|LG5

Nucleotide

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