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PDGFRA Invitrogen Lab (UK) kinase screen (BI)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of PDGFRa (unknown origin) at 10 uM by biochemical hotspot kinase assay
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of PDGFRalpha (unknown origin) preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of PDGFRalpha (unknown origin) assessed as residual activity at 1 uM preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay relative to control
Inhibition of PDGFRalpha (unknown origin) at 1 uM relative to control
Inhibition of GST-tagged human recombinant PDGFR-alpha (550 to 1089 residues) expressed in baculovirus expression system at 200 nM by Z'-lyte assay
Inhibition of PDGFRalpha (unknown origin) incubated for 1.5 hrs in the presence of ATP by Z'-LYTE kinase assay
Inhibition of recombinant PDGFRalpha (unknown origin) incubated for 60 mins by ELISA analysis
Inhibition of PDGFRalpha (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of PDGFRalpha D842V mutant (unknown origin)
Selectivity interaction (Kinase Profiler (Millipore)) EUB0000603a PDGFRA
Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000321b PDGFRA
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000321b PDGFRA
Selectivity interaction (SelectScreen (Invitrogen)) EUB0000679a PDGFRA
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a PDGFRA
Inhibition of PDGFRA (unknown origin) at 1 uM in presence of ATP by Z'-LYTE assay relative to control
Assay data:2 Tested
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