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Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
SummaryPubMed Citation
Inhibition of human NTPDase-3 using ATP as substrate assessed as inorganic phosphate release at 100 uM after 15 mins relative to control
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by Target
Drug metabolism assessed as human NTPDase-3-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis
Assay data:1 Tested
Drug metabolism assessed as human NTPDase-3-mediated compound hydrolysis expressed in African green monkey COS7 cells at 100 uM after 1 hr by HPLC analysis relative to ATP
Assay data:6 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Inhibition of human NTPDase3 assessed as amount of inorganic phosphate released using ATP as the substrate preincubated at 100 uM for 3 mins before substrate addition after 15 mins by malachite green reagent method
Assay data:9 Tested
Drug metabolism assessed as human nucleotide triphosphate diphosphohydrolase3-mediated compound hydrolysis at 4.24 mM after 1 hr by HPLC analysis relative to ADP
Assay data:4 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Inhibition of human NTPDase3 expressed in COS7 cells assessed as amount of inorganic phosphate released using ATP as the substrate at 100 uM after 15 mins by malachite green reagent method
Activity of human NTPDase3 expressed in COS7 cells assessed as amount of inorganic phosphate released using ATP as the substrate at 100 uM after 15 mins by malachite green reagent method
Inhibition of human NTPdase3 by capillary electrophoresis method
Assay data:3 Tested
Inhibition of human NTPDase 3 expressed in human 293T cells
Activity of human NTPDase 3 expressed in human 293T cells assessed as drug hydrolysis at 100 uM after 20 mins relative to ATP
Inhibition of human NTPDase 3 expressed in COS7 cells at 1mM
Assay data:13 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Activation of human NTPDase3 using ATP as substrate preincubated for 3 mins followed by substrate addition measured after 10 mins by malachite green reagent-based assay relative to control
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