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Inhibition of human full length recombinant CDK13/cyclinK at 1 uM using RSRSRSRSRSRSRSR as substrate incubated for 120 mins in presence of [gamma-33P]ATP at by radiometric assay relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Competitive irreversible inhibition of CDK13/cyclinK (unknown origin) in presence of Km ATP
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Competitive irreversible inhibition of CDK12/cyclinK (unknown origin) in presence of Km ATP
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Competitive irreversible inhibition of CDK13/cyclinK (unknown origin) in presence of 1 mM ATP
Competitive irreversible inhibition of CDK12/cyclinK (unknown origin) in presence of 1 mM ATP
Inhibition of CDK9/Cyclin K (unknown origin) at 1 uM relative to control
Inhibition of tracer 236 binding to human GST/His-tagged CDK13/Cyclin K at 0.1 uM
Assay data:2 Tested
Inhibition of recombinant full length human CDK13/cyclinK using RSRSRSRSRSRSR as substrate incubated for 120 mins in presence of [gamma-33ATP] by radiometric scintillation counting analysis
Inhibition of recombinant full length human CDK12/cyclinK using RSRSRSRSRSRSR as substrate incubated for 120 mins in presence of [gamma-33ATP] by radiometric scintillation counting analysis
Inhibition of full-length recombinant human CDK12/cyclinK at 10 uM using RSRSRSRSRSRSRSR as substrate after 40 mins by in presence of [gamma33P]ATP by scintillation counting method relative to control
Inhibition of full-length recombinant human CDK13/cyclinK at 10 uM using RSRSRSRSRSRSRSR as substrate after 120 mins by in presence of [gamma33P]ATP by scintillation counting method relative to control
Inhibition of recombinant human full-length N-terminal GST-tagged CDK9/cyclinK expressed in baculovirus infected Sf9 insect cells using PDKtide as substrate measured after 120 mins by ADP-glo assay
Assay data:26 Active, 13 Activity ≤ 1 µM, 60 Tested
Inhibition of human full length recombinant CDK12/cyclinK at 1 uM using RSRSRSRSRSRSRSR as substrate incubated for 120 mins in presence of [gamma-33P]ATP at by radiometric assay relative to control
Inhibition of human CDK9/cyclin-K at 100 nM using KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC as substrate by [gamma-33P]-ATP assay
Inhibition of human CDK9/cyclin-K at 10 uM using KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC as substrate in presence of [gamma-33P]-ATP
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of recombinant full length human CDK13/cyclinK at 10 uM using RSRSRSRSRSRSRSR as substrate measured after 120 mins in presence of [gamma33P]ATP by scintillation counting method
Inhibition of recombinant full length human CDK12/cyclinK at 10 uM using RSRSRSRSRSRSRSR as substrate measured after 120 mins in presence of [gamma33P]ATP by scintillation counting method
Inhibition of human recombinant full length His-tagged CDK9/cyclin K expressed in baculovirus expression system
Inhibition of recombinant full length human CDK13/cyclinK assessed as residual activity at 10 uM using RSRSRSRSRSRSR as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control
Inhibition of recombinant full length human CDK12/cyclinK assessed as residual activity at 10 uM using RSRSRSRSRSRSR as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control
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