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Inhibition of PDE8B (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of cAMP-specific 3',5'-cyclic phosphodiesterase (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested
Inhibition of human PDE4 at 10 uM relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP Assay
Assay data:8 Active, 8 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
Inhibition of PDE8B (unknown origin) at 10 uM relative to control
Inhibition of PDE (unknown origin)
Inhibition of human PDE
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of full length recombinant human PDE8B using 3',5'-[3H]cAMP as substrate after 30 mins by scintillation proximity assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of full length human recombinant PDE8B using [3H]-cAMP as substrate by scintillation proximity assay
Inhibition of human PDE8B
SummaryCompounds, ActiveRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Inhibition of PDE8 (unknown origin)
Inhibition of PDE8 (unknown origin) at 1 uM
Assay data:2 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
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