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RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
SummaryPubMed Citation
Inhibition of cdk-mediated Rb phosphorylation at thr821 in human A2780 cells at 10 uM after 24 hrs
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human CDK10 in HL60 cells lysate at 10 uM using post probe-labeling by LC-MS/MS analysis relative to control
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by Target
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
AT1R-EGFR transactivation kinome screen - primary
Assay data:50 Active, 714 Tested
Inhibition of CDK (unknown origin) expressed in human ARN8 cells assessed as increase in p53-dependent transcriptional activity after 24 hrs by beta-galactosidase reporter gene assay
Assay data:7 Active, 15 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Tertiary Screen (multiple cell lines)
Assay data:105 Active, 106 Tested
Inhibition of cdk-mediated NPM phosphorylation at thr199 in human A2780 cells at 10 uM
RNAi screen for vorinostat resistance genes - Secondary Deconvolution Screen
Assay data:732 Active, 1804 Tested
Inhibition of CDK10 in human PC3 cell lysates at 10 uM using desthiobiotin-tagged ATP probe AX9989 followed by trypsinization by LC/MS analysis
Assay data:12 Tested
Inhibition of CDK10 in human PC3 cell lysates at 30 uM using desthiobiotin-tagged ATP probe AX9989 followed by trypsinization by LC/MS analysis
Assay data:4 Tested
Human kinome siRNA screen in A549-BTR and MDA-231-1833-BTR cells
Assay data:49 Active, 714 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Inhibition of CDK in human A2780 cells assessed as accumulation of hypophosphorylated form of retinoblastoma protein at 1 uM by immunohistochemistry
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