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Inhibition of GST-tagged human MLL2 (958 to 1014 residues) expressed in Escherichia coli BL21 cells a incubated for 30 mins by fluorescence polarization assay
Assay data:9 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant N-terminal his-tagged MLL2 (5319 to 5537 residues) expressed in Escherichia coli at 50 uM in presence of [3H]-SAM by scintillation/filter assay relative to control
Assay data:1 Tested
Inhibition of human recombinant N-terminal his-tagged MLL2 (5319 to 5537 residues) expressed in Escherichia coli at 10 uM in presence of [3H]-SAM by scintillation/filter assay
Inhibition of recombinant human N- terminal His-tagged MLL2 (5319 to 5537 residues) expressed in Escherichia coli using core histone as substrate at 10 uM by radiometric HotSpot assay relative to control
Inhibition of MLL2 (unknown origin) using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by Alphalisa assay
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of MLL4 (unknown origin) H3K4 methyltransferase activity using biotinyl-H3 peptide (1 to 21 residues) and using [3H]-S adenosylmethionine as methyl donor up to 100 uM after 1 hr by scintillation counting
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Assay data:478 Active, 1380 Tested
Inhibition of MLL2 using core histone as substrate preincubated for 10 mins followed by addition of [3H]SAM and incubated for 60 mins
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Chromatin factor siRNA screen in epidermal stem cells
Assay data:97 Active, 331 Tested
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