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RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
SA11 PAX8: cytotoxicity OVCAR4 Measured in Cell-Based System Using Plate Reader - 7054-13_Inhibitor_Dose_DryPowder_Activity
Assay data:75 Active, 6 Activity ≤ 1 µM, 140 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
SA8-Pax8: cytotoxicity OV-90 Measured in Cell-Based System Using Plate Reader - 7054-10_Inhibitor_Dose_DryPowder_Activity
Assay data:89 Active, 4 Activity ≤ 1 µM, 140 Tested
SA7-Pax8: cytotoxicity COV434 Measured in Cell-Based System Using Plate Reader - 7054-09_Inhibitor_Dose_DryPowder_Activity
Assay data:100 Active, 4 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 140 Tested
SA12 PAX8: cytotoxicity COV362 Measured in Cell-Based System Using Plate Reader - 7054-16_Inhibitor_Dose_DryPowder_Activity
Assay data:78 Active, 2 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 140 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
SA5-Pax8: Cytotoxicity IOSE-T80 Measured in Cell-Based System Using Plate Reader - 7054-07_Inhibitor_Dose_CherryPick_Activity
Assay data:123 Active, 80 Activity ≤ 1 µM, 1810 Tested
PAX8: PAX8-dependent cytoxicity Measured in Cell-Based System Using Plate Reader - 7054-06_Inhibitor_Dose_CherryPick_Activity
Assay data:150 Active, 113 Activity ≤ 1 µM, 1730 Tested
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_Dose_CherryPick_Activity
Assay data:1637 Active, 118 Activity ≤ 1 µM, 1810 Tested
Broad Institute Discovering modulators of PAX8 for targeting ovarian cancer Inhibitor Probe Project
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_SinglePoint_HTS_Activity
Assay data:4162 Active, 356682 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
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