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TLR-pathway-human_FLG ligand_TNF readout
Assay data:142 Active, 756 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
SummaryPubMed Citation
Agonist activity at human recombinant TLR3 expressed in HEK293 cells at 10 uM by SEAP reporter assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
TLR-pathway-human_P2C ligand_TNF readout
Assay data:130 Active, 756 Tested
TLR-pathway-human_PGN ligand_TNF readout
Assay data:143 Active, 756 Tested
TLR-pathway-human_LPS ligand_TNF readout
Assay data:140 Active, 756 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
TLR-pathway-human_R848 ligand_TNF readout
Assay data:134 Active, 756 Tested
TLR-pathway-human_P3C ligand_TNF readout
Agonist activity at human TLR3 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid handler-assisted reporter gene assay
Assay data:33 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Antagonist activity at human TLR3 expressed in HEK293 cells assessed as decrease in poly I:C-induced NF-kappaB activation-mediated SEAP production at 10'-9 to 10'-5 M after 24 hrs by Quanti-blue-based assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at human TLR3 expressed in HEK-Blue assessed as inhibition of poly 1:C-induced NF-kappaB activation-mediated SEAP production at 25 uM after 24 hrs by Quanti-blue-based assay
Activity at human TLR3 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter activity by measuring increase in secreted alkaline phosphatase level by spectrophotometric method
Assay data:38 Tested
Agonist activity at human TLR3 HEK-Blue cells assessed as increase in NFkappaB activation by sAP reporter gene assay
Assay data:16 Tested
RNAi Global Initiative pilot viability screen of human kinase and cell cycle genes
Assay data:5 Active, 840 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
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