BioAssay by Target (List) for Gene (Select 7075) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 74

<< First< Prev

Page of 4

Select item 19149781.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000336a TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1914978

Summary Related BioAssays by Target

Select item 19135792.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000147b TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1913579

Summary Related BioAssays by Target

Select item 19131823.

Affinity Biochemical interaction (KdELECT (DiscoverX)) EUB0000713a TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913182

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19129284.

Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000713a TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912928

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19129105.

Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000703a TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912910

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18493586.

Binding affinity to TIE1 (unknown origin) assessed as dissociation constant by competition binding assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1849358

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18354527.

TIE1 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1835452

Summary Related BioAssays by Target

Select item 18205378.

Binding affinity to wild-type human partial length TIE1 (T819 to A1138 residues) expressed in bacterial expression system by Kinomescan method

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1820537

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 17943649.

KinomeScan assay: inhibition of TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:2 Active, 108 Tested

AID:: 1794364

Summary Compounds, Active Related BioAssays by Target

Select item 178965410.

NanoBRET assay (SGC) with TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1789654

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 178964711.

NanoBRET assay (SGC) with TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1789647

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 178963512.

KINOMEScan (DiscoveRx Corp) with TIE1

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1789635

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 177490713.

Inhibition of TIE1 (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell proliferation assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:2 Active, 3 Tested

AID:: 1774907

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 174837614.

Inhibition of human TIE1 assessed as percent of control at 2000 nM by KINOMEscan assay relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1748376

Summary Related BioAssays by Target

Select item 174781115.

Inhibition of DNA-tagged human TIE1 assessed as percent of control at 50000 nM by qPCR analysis relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1747811

Summary Related BioAssays by Target

Select item 174735916.

Inhibition of human TIE1 assessed as percent of control at 1000 nM by KINOMEscan assay relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1747359

Summary Related BioAssays by Target

Select item 174677117.

Inhibition of human TIE1 assessed as percent of control at 2000 nM by KINOMEscan assay relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1746771

Summary Related BioAssays by Target

Select item 174129518.

Inhibition of wild-type human partial length TIE1 (T819 to A1138 residues) expressed in bacterial expression system assessed as residual activity at 1 uM by Kinomescan method relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1741295

Summary PubMed Citation Related BioAssays by Target

Select item 174126119.

Binding affinity to wild-type human partial length TIE1 (T819 to A1138 residues) expressed in bacterial expression system by Kinomescan method relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1741261

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 173172620.

Inhibition of human partial length TIE1 (T819 to A1138 residues) expressed in bacterial expression system assessed as residual activity at 10 uM by kinome scan method relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase receptor Tie-1

Assay data:1 Tested

AID:: 1731726

Summary PubMed Citation Related BioAssays by Target

<< First< Prev

Page of 4

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (19)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (6)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (14)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (16)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (10)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (59)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (15)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (43)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (28)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 7075) (74)
PubChem BioAssay

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay