BioAssay by Target (List) for Gene (Select 6850) - PubChem BioAssay - NCBI

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Select item 7415161.

Inhibition of SYK (unknown origin) assessed as remaining activity at 10 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:2 Tested

AID:: 741516

Summary PubMed Citation Related BioAssays by Target

Select item 7732162.

Inhibition of human SYK assessed as residual activity at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:3 Tested

AID:: 773216

Summary PubMed Citation Related BioAssays by Target

Select item 7700183.

Inhibition of spleen tyrosine kinase (unknown origin)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:27 Active, 21 Activity ≤ 1 µM, 33 Tested

AID:: 770018

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 7692684.

Competitive binding affinity to SYK (unknown origin) at 10 uM in presence of ATP relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:6 Tested

AID:: 769268

Summary PubMed Citation Related BioAssays by Target

Select item 7670835.

Inhibition of SYK (unknown origin) at 30 uM by microfluidic mobility shift assay relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:3 Tested

AID:: 767083

Summary PubMed Citation Related BioAssays by Target

Select item 7580036.

Inhibition of SYK (unknown origin) after 60 mins

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:1 Active, 1 Tested

AID:: 758003

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 7570787.

Inhibition of SYK (unknown origin) at 10 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:1 Tested

AID:: 757078

Summary PubMed Citation Related BioAssays by Target

Select item 7521588.

Inhibition of SYK (unknown origin) transfected in mouse Ba/F3 cells at 1 uM after 24 hrs

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:3 Tested

AID:: 752158

Summary PubMed Citation Related BioAssays by Target

Select item 7521349.

Inhibition of SYK (unknown origin) transfected in mouse Ba/F3 cells at 5 uM after 24 hrs

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:2 Tested

AID:: 752134

Summary PubMed Citation Related BioAssays by Target

Select item 74494310.

Inhibition of SYK (unknown origin) at 10 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:6 Tested

AID:: 744943

Summary PubMed Citation Related BioAssays by Target

Select item 74345411.

RNAi screen for vorinostat resistance genes - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:450 Active, 18118 Tested

AID:: 743454

Summary PubMed Citation

Select item 74312112.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

Select item 77324713.

Inhibition of human SYK assessed as residual activity at 10 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:3 Tested

AID:: 773247

Summary PubMed Citation Related BioAssays by Target

Select item 74085314.

Inhibition of SYK (unknown origin) at 1 uM by single point assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:2 Tested

AID:: 740853

Summary PubMed Citation Related BioAssays by Target

Select item 74081215.

Inhibition of SYK (unknown origin) at 10 uM by single point assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:1 Tested

AID:: 740812

Summary PubMed Citation Related BioAssays by Target

Select item 74047816.

Inhibition of SYK (unknown origin) assessed as remaining activity at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:1 Tested

AID:: 740478

Summary PubMed Citation Related BioAssays by Target

Select item 73913717.

Inhibition of SYK (unknown origin) using [gamma-33P]ATP assessed as residual activity at 3 uM

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:1 Tested

AID:: 739137

Summary PubMed Citation Related BioAssays by Target

Select item 73728218.

Inhibition of Syk (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:1 Tested

AID:: 737282

Summary PubMed Citation Related BioAssays by Target

Select item 73718919.

Inhibition of human recombinant truncated SYK (360 to 365 amino acid residues) using N-terminally biotinylated EPEGDYEEVLE peptide as substrate assessed as inhibition of [33P]-ATP incorporation incubated for 10 mins prior to substrate addition measured after 15 mins by scintillation counting

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:41 Active, 2 Activity ≤ 1 nM, 41 Activity ≤ 1 µM, 41 Tested

AID:: 737189

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 73718520.

Inhibition of SYK in human Ramos cells

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase SYK

Assay data:38 Active, 30 Activity ≤ 1 µM, 39 Tested

AID:: 737185

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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BioAssays with protein sequences specified as targets
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BioAssays with gene sequences specified as RNAi targets and the activity is active

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BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (69)
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Activity (IC50, etc) ≤ 1 µM (256)
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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
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Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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BioAssays extracted from the literature
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BioAssay by Target (List) for Gene (Select 6850) (755)
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Acute Picornavirus-induced exacerbation in asthmatic children: nasal lavage cell...
Acute Picornavirus-induced exacerbation in asthmatic children: nasal lavage cells
Accession: GDS4424

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Related DataSets for GEO Profiles (Select 89668228) (1)
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