BioAssay by Target (List) for Gene (Select 649) - PubChem BioAssay - NCBI

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Select item 1616371.

Inhibitory activity against Procollagen C-terminal proteinase (PCP); Not tested

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:2 Tested

AID:: 161637

Summary PubMed Citation Related BioAssays by Target

Select item 7189362.

Inhibition of PCP after 1 hr by fluorescence assay

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:35 Active, 19 Activity ≤ 1 µM, 63 Tested

AID:: 718936

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 7189353.

Inhibition of PCP at 10 uM after 1 hr by fluorescence assay

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:3 Tested

AID:: 718935

Summary PubMed Citation Related BioAssays by Target

Select item 7189304.

Inhibition of PCP in HFF cells assessed as inhibition of collagen deposition after 48 hrs by ELISA

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 718930

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6518115.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 6518106.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 6240997.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 3709338.

Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation counting

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 370933

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3709289.

Inhibition of human procollagen C-proteinase expressed in CHO cells by fluorescence assay

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:23 Active, 21 Activity ≤ 1 µM, 24 Tested

AID:: 370928

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 34463210.

Inhibition of BMP1

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 344632

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 29211011.

Inhibition of human procollagen C-proteinase expressed in CHO cells

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:70 Active, 68 Activity ≤ 1 µM, 70 Tested

AID:: 292110

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 74312112.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

Select item 16163613.

Ability to inhibit procollagen C-terminal proteinase (PCP) tested in vitro

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:38 Active, 36 Activity ≤ 1 µM, 44 Tested

AID:: 161636

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16163514.

Inhibitory activity against Procollagen C-terminal proteinase (PCP)at a concentration of 100 (uM)

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:1 Tested

AID:: 161635

Summary PubMed Citation Related BioAssays by Target

Select item 16163415.

The compound was evaluated for its inhibitory effect against Procollagen C-terminal proteinase

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 161634

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16163316.

Inhibitory effect against Procollagen C-terminal proteinase

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:50 Active, 40 Activity ≤ 1 µM, 62 Tested

AID:: 161633

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16163217.

Inhibitory activity against procollagen C-proteinase (PCP).

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:37 Active, 37 Activity ≤ 1 µM, 37 Tested

AID:: 161632

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16163118.

Inhibitory activity against Procollagen C-terminal proteinase (PCP)

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:1 Tested

AID:: 161631

Summary PubMed Citation Related BioAssays by Target

Select item 16163019.

In vitro inhibitory activity against procollagen C-terminal proteinase (PCP) in HT1080 cells using synthetic peptide as substrate

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:19 Active, 16 Activity ≤ 1 µM, 19 Tested

AID:: 161630

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 16162920.

Inhibitory activity against Procollagen C-Proteinase (PCP)

Source:: ChEMBL

Protein Target:: Bone morphogenetic protein 1

Assay data:42 Active, 2 Activity ≤ 1 nM, 42 Activity ≤ 1 µM, 42 Tested

AID:: 161629

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (21)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (3)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (21)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (22)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (30)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (24)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (18)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 649) (43)
PubChem BioAssay
RMST rhabdomyosarcoma 2 associated transcript [Homo sapiens]
RMST rhabdomyosarcoma 2 associated transcript [Homo sapiens]
Gene ID:196475

Gene
196475[uid] AND (alive[prop]) (1)
Gene
bone morphogenetic protein 1 isoform 1 precursor [Homo sapiens]
bone morphogenetic protein 1 isoform 1 precursor [Homo sapiens]
gi|4502421|ref|NP_001190.1|

Protein
Homo sapiens rhabdomyosarcoma 2 associated transcript (RMST), transcript variant...
Homo sapiens rhabdomyosarcoma 2 associated transcript (RMST), transcript variant 29, long non-coding RNA
gi|2515629315|ref|NR_186078.1|

Nucleotide

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