BioAssay by Target (List) for Gene (Select 640) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 391

<< First< Prev

Page of 20

Select item 19564651.

Inhibition of His-tagged human recombinant BLK expressed in insect cells at 200 nM by Z'-lyte assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1956465

Summary PubMed Citation Related BioAssays by Target

Select item 19544772.

Inhibition of BLK (unknown origin) by Z'LYTE assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1954477

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19544683.

Inhibition of BLK (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1954468

Summary PubMed Citation Related BioAssays by Target

Select item 19544604.

Inhibition of BLK (unknown origin) assessed as ratio of Kinact/Ki

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:3 Tested

AID:: 1954460

Summary PubMed Citation Related BioAssays by Target

Select item 19544465.

Inhibition of BLK (unknown origin) incubated for 1 hr in presence of ATP by Z'LYTE assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1954446

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19513126.

Inhibition of BLK (unknown origin) at 500 nM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1951312

Summary PubMed Citation Related BioAssays by Target

Select item 19482287.

Inhibition of human BLK preincubated for 1 hrs followed by substrate addition and measured after 1 hrs in the presence of ATP at Km concentration by TR-FRET assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1948228

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19465208.

Binding affinity to BLK (unknown origin) assessed as strong interaction at 100 nM

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Active, 1 Tested

AID:: 1946520

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19354679.

Inhibition of human BLK at 1 uM by hotspot assay relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1935467

Summary PubMed Citation Related BioAssays by Target

Select item 192135710.

Induction of BLK degradation in human K562 cells assessed as maximum degradation relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1921357

Summary PubMed Citation Related BioAssays by Target

Select item 192135611.

Induction of BLK degradation in human K562 cells

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1921356

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 191918612.

HotSpot Assay from US Patent US11542261: "Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors"

Source:: BindingDB

Protein Targets:: Cyclin-H; ...
Total:: 10

Assay data:30 Active, 6 Activity ≤ 1 nM, 30 Activity ≤ 1 µM, 30 Tested

AID:: 1919186

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191547413.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000596aBDA BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1915474

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191488714.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000252b BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1914887

Summary Related BioAssays by Target

Select item 191421415.

Selectivity interaction (Kinase panel (ProQinase, FlashPlate?-based radiometric assay, 10 M ATP)) EUB0000006b BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1914214

Summary Related BioAssays by Target

Select item 191368216.

Selectivity interaction (Z?-LYTE assay) EUB0000638a BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1913682

Summary Related BioAssays by Target

Select item 191357117.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000147b BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1913571

Summary Related BioAssays by Target

Select item 191351718.

Selectivity interaction (Ambit kinome screening platform (Ambit phage-based competition binding assay)) EUB0000624a BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Tested

AID:: 1913517

Summary Related BioAssays by Target

Select item 191310219.

Affinity Biochemical interaction (33P-ATP and filter-binding assay (Reaction Biology)) EUB0000646a BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913102

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191268920.

Affinity Phenotypic Cellular interaction (CellTiter-Glo Luminescent Cell Viability Assay (Promega; growth inhibitory activity in Rec-1 cells)) EUB0000646a BLK

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase Blk

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912689

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

<< First< Prev

Page of 20

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (9)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (119)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (24)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (96)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (126)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (40)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (345)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (46)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (309)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (79)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 640) (391)
PubChem BioAssay

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay