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Inhibition of renin activity in human plasma by competitive radio immunoassay
Assay data:7 Active, 7 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRET
Assay data:16 Active, 2 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 23 Tested
Inhibition of human recombinant renin using sheep recombinant angiotensinogen substrate incubated for 1 hr by EIA
Assay data:1 Active, 1 Activity ≤ 1 µM, 7 Tested
Inhibition of renin activity in human plasma
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human recombinant renin
Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of recombinant glycosylated human renin expressed in CHO cells
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of human plasma renin
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of recombinant human renin
Displacement of 125I-labeled angiotensin I from from human plasma renin by gamma counter based competitive radioimmunoassay
Assay data:10 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluorescent quenching substrate incubated for 1 hr by FRET analysis
Assay data:14 Active, 4 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 16 Tested
Inhibition of human renin
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human renin preincubated for 5 mins followed by substrate addition by fluorometer analysis
Assay data:3 Active, 1 Activity ≤ 1 µM, 4 Tested
Peptidase, Renin Eurofins-Panlabs enzyme assay
SummaryRelated BioAssays by Target
Inhibition of human renin assessed as inhibition constant using H-R-E(EDANS)-1HPFHLVIHT-K(DABCYL)-R-OH as susbtrate by spectrophotometric analysis
Inhibitory Assay from US Patent US9278944: "Nitrogen-containing saturated heterocyclic compound"
Assay data:128 Active, 9 Activity ≤ 1 nM, 128 Activity ≤ 1 µM, 128 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition Assay from US Patent US8975252: "Morpholine derivative"
FRET Assay from US Patent US8497286: "Organic compounds"
Assay data:17 Active, 11 Activity ≤ 1 nM, 17 Activity ≤ 1 µM, 17 Tested
Enzyme Inhibition Assay from Article 10.1016/j.bmc.2008.08.012: "Achiral oligoamines as versatile tool for the development of aspartic protease inhibitors."
Assay data:7 Active, 1 Activity ≤ 1 µM, 11 Tested
Fluorescence Resonance Energy Transfer (FRET) Assay from Article 10.1016/j.bmcl.2009.04.140: "Design and optimization of renin inhibitors: Orally bioavailable alkyl amines."
Assay data:34 Active, 6 Activity ≤ 1 nM, 34 Activity ≤ 1 µM, 34 Tested
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