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Activation of PKC in human HeLa cells assessed as induction of ERK1/2 phosphorylation after 1 to 20 mins by Western blot in presence of MEK inhibitor U0126
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human PKCepsilon
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of PKCepsilon by fluorescence polarization assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of PRKCE at 3 uM
Assay data:1 Tested
Inhibition of human PKCepsilon type M486A mutant
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 3 Tested
Antagonist activity at protein kinase C epsilon
Agonist activity at protein kinase C epsilon at 50 pg/mL
Inhibition of human PKCepsilon by IMAP assay
Inhibition of PKC in human HeLa cells assessed as blockade of PMA-evoked ERK1/2 phosphorylation by Western blot
Inhibition of PKCepsilon at 100 nM relative to control
Activation of PKC in human HeLa cells assessed as induction of ERK1/2 phosphorylation after 1 to 20 mins by Western blot
Assay data:2 Active, 3 Tested
Inhibition of human full length PKCepsilon
Inhibition of PKCepsilon at 1 uM
Inhibition of human PKC expressed in baculovirus insect cell system
Inhibition of PKCepsilon
Displacement of [3H]PDBu form human PKCepsilon in presence of plasma membrane lipid mimetic mixture
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Displacement of [3H]PDBu form human PKCepsilon in presence of phosphatidylserine
Activation of PKC in PMA-stimulated human LNCAP cells assessed as ERK phosphorylation at 1 nM to 10 uM by Western blot relative to PMA
Assay data:4 Active, 4 Tested
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