BioAssay by Target (List) for Gene (Select 5568) - PubChem BioAssay - NCBI

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Select item 19608751.

Inhibition of PKA (unknown origin) at 10 uM by biochemical hotspot kinase assay

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1960875

Summary Related BioAssays by Target

Select item 19593602.

Inhibition of PKA (unknown origin) using Kemptide as substrate incubated for [gamma-32P]-ATP incubated for 5 mins by scintillation counter analysis

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Active, 1 Tested

AID:: 1959360

Summary Related BioAssays by Target

Select item 19583793.

Inhibition of PKA (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:3 Tested

AID:: 1958379

Summary Related BioAssays by Target

Select item 19531734.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:8 Active, 2 Activity ≤ 1 µM, 11 Tested

AID:: 1953173

Summary Related BioAssays by Target

Select item 19413285.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1941328

Summary Related BioAssays by Target

Select item 19410626.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941062

Summary Related BioAssays by Target

Select item 19410597.

Inhibition of PKA (unknown origin) assessed as fold increase

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1941059

Summary Related BioAssays by Target

Select item 19322818.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1932281

Summary Related BioAssays by Target

Select item 19218709.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:3 Active, 2 Activity ≤ 1 µM, 22 Tested

AID:: 1921870

Summary Related BioAssays by Target

Select item 192086010.

Inhibition of human PKA

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit gamma; ...
Total:: 3

Assay data:1 Active, 1 Tested

AID:: 1920860

Summary Related BioAssays by Target

Select item 190244511.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1902445

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190240612.

Inhibition of PKA (unknown origin) at 50 nM by Z'LYTE screening method relative to control

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:3 Tested

AID:: 1902406

Summary PubMed Citation Related BioAssays by Target

Select item 189995313.

Inhibition of human PKA at 10 uM by radiometric kinase activity assay relative to control

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1899953

Summary PubMed Citation Related BioAssays by Target

Select item 189995214.

Inhibition of human PKA at 0.1 uM by radiometric kinase activity assay relative to control

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1899952

Summary PubMed Citation Related BioAssays by Target

Select item 189829915.

Inhibition of human PKA assessed as residual activity at 30 uM relative to control

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1898299

Summary PubMed Citation Related BioAssays by Target

Select item 188903816.

Inhibition of PKA (unknown origin) at 1.0 uM relative to control

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1889038

Summary PubMed Citation Related BioAssays by Target

Select item 188704417.

Activation of PKA substrate phosphorylation in HEK293 cells incubated for 60 mins by Western blot analysis

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Active, 1 Tested

AID:: 1887044

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 188395518.

Inhibition of PKA (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Tested

AID:: 1883955

Summary PubMed Citation Related BioAssays by Target

Select item 188116319.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:2 Active, 1 Activity ≤ 1 µM, 4 Tested

AID:: 1881163

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 187603820.

Inhibition of PKA (unknown origin)

Source:: ChEMBL

Protein Targets:: cAMP-dependent protein kinase catalytic subunit alpha; ...
Total:: 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1876038

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (61)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (6)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (49)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (119)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (40)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (206)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (44)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (198)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (50)
BioAssays deposited by other experimentalists

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