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RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
SummaryPubMed Citation
Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based spectrophotometry assay
Assay data:7 Active, 3 Activity ≤ 1 µM, 17 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Flag-tagged p53/GST-tagged PPID (unknown origin) expressed in Escherichia coli BL21 after 1 hr by ELISA microplate reader method
Assay data:10 Tested
SummaryPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Binding affinity to Cyclophilin D (unknown origin) by isothermal titration calorimetry
Assay data:8 Active, 2 Activity ≤ 1 µM, 17 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Inhibition of fluorescein labeled cyclosporin binding to Cyp40 by fluorescence polarization competition assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of cyclosporin binding to Cyp40 by fluorescence polarization competition assay
Inhibition of Cyclophilin 40 PPIase activity
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Binding affinity to CypD (unknown origin) assessed as dissociation constant by SPR analysis
Binding affinity to CypD (unknown origin)
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Enzymatic Assay from US Patent US8901295: "Inhibitors of cyclophilins and uses thereof"
Assay data:11 Active, 3 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
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