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Binding affinity to exonuclase deficient human recombinant DNA polymerase gamma E200A mutant
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human DNA polymerase gamma at 100 uM
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human DNA polymerase gamma
Assay data:2 Tested
Inhibition of human DNA polymerase gamma by microplate reader analysis
Assay data:4 Tested
Inhibition of human DNA polymerase gamma assessed as incorporation of [alpha-32P]dCTP up to 1mM preincubated for 30 mins by whatman DE81 paper binding assay
Assay data:3 Tested
Inhibition of human recombinant DNA polymerase gamma by scintillation counting
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Ratio of polymerization constant K to Kd for human recombinant DNA polymerase gamma E200A mutant
Polymerizing activity of exonuclase deficient human recombinant DNA polymerase gamma E200A mutant assessed as rate of nucleotide incorporation by pre-steady state single nucleotide incorporation assay
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Assay data:1 Active, 1 Tested
Inhibition of human gamma polymerase
Inhibition of DNA polymerase gamma
Inhibitory activity against human mitochondrial DNA polymerase gamma upto 50 uM
Inhibition of human gamma DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C; nd is not determined
Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)
Assay data:4 Active, 1 Activity ≤ 1 µM, 5 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
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