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Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Dissociation constant for [3H]ORG2058 at human progesterone receptor at 273 K
Dissociation constant for [3H]ORG2058 at human progesterone receptor at 303 K
Agonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell line
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Transcriptional activation in cells expressing progesterone receptor isoform B compared to progesterone
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity for progesterone receptor
Assay data:4 Active, 2 Activity ≤ 1 µM, 9 Tested
Antagonist activity against progesterone receptor (PR) using PRE-luciferase plasmid co-transfected CV-1 cells
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cells
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell line
Assay data:11 Active, 1 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 11 Tested
Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell line
Assay data:13 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 16 Tested
Dissociation constant for [3H]-ORG2058 at human progesterone receptor at 278 K
Effective concentration of progesterone receptor agonist induction of alkaline phosphatase activity in human T47D breast carcinoma cells
Assay data:30 Active, 7 Activity ≤ 1 nM, 28 Activity ≤ 1 µM, 32 Tested
Effective concentration on alkaline phosphatase activity in human T47D breast carcinoma cell line.
Assay data:39 Active, 9 Activity ≤ 1 nM, 39 Activity ≤ 1 µM, 48 Tested
Agonistic activity as progesterone receptor induced alkaline phosphatase activity in T47D human breast cancer cells
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Relative binding affinity against progestin receptor
Assay data:47 Tested
Relative binding affinity for progestin receptor of uterus of rabbit at 24 hr
Assay data:39 Tested
Relative binding affinity for progesterone receptor in MCF-7 cell cytosol extract
Assay data:6 Tested
Inhibition of transcriptional activation in cells expressing progesterone receptor isoform B
Assay data:3 Tested
Displacement of [3H]progesterone from human Progesterone receptor
Assay data:12 Active, 8 Activity ≤ 1 µM, 12 Tested
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