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Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Assay data:20 Active, 1 Activity ≤ 1 µM, 31 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
RNAi Global Initiative pilot viability screen of human kinase and cell cycle genes
Assay data:5 Active, 840 Tested
Summary
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Assay data:478 Active, 1380 Tested
Inhibition of PCNA in human U2OS cells assessed as cisplatin-induced DNA damage at 25 uM after 22 hrs by comet assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of PCNA in human HeLa cells assessed as increase in histone H2AX phosphorylation at 10 uM after 18 hrs by flow cytometric analysis in absence of cisplatin
Assay data:9 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of PCNA in human cisplatin-damaged HeLa cells assessed as increase in histone H2AX phosphorylation at 10 uM after 18 hrs by flow cytometric analysis
Assay data:9 Active, 9 Tested
Inhibition of PCNA in human GM14931 cells expressing truncated X-PG transfected with aqueous acid-treated pGL4 assessed as inhibition of translation DNA synthesis-mediated repair of cisplatin-damaged plasmid at 10 uM after 72 hrs by luciferase reporter assay
Assay data:3 Tested
Inhibition of PCNA in human HeLa cells expressing X-PG assessed as inhibition of translation DNA synthesis-mediated repair of cisplatin-damaged plasmid at 10 uM after 72 hrs by luciferase reporter assay
Assay data:12 Tested
Inhibition of PCNA in human GM14931 cells expressing truncated X-PG assessed as inhibition of translation DNA synthesis-mediated repair of cisplatin-damaged plasmid at 10 uM after 72 hrs by luciferase reporter assay
Assay data:12 Active, 12 Tested
Inhibition of PCNA-mediated cell cycle progression in human BPH-1 cells assessed as reduction in cyclin D level at 250 to 500 uM after 24 hrs by immunoblot analysis
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
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