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Inhibition of fatty acid synthase in rat cytosolic hepatic extracts using acetyl CoA and malonyl CoA as substrate preincubated for 30 mins followed by acetyl CoA addition and subsequent incubation for 3 mins prior to malonyl CoA addition measured after 10 mins in presence of NADPH by spectrophotometric method
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of rat FASN assessed as release of co-enzyme A
Assay data:14 Active, 7 Activity ≤ 1 µM, 21 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of FASN in rat NMU cells assessed as reduction of de novo synthesis of palmitate
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of FASN in rat liver
Assay data:1 Tested
Inhibition of rat liver FAS at 60 uM by Coomassie blue staining
Assay data:8 Tested
Inhibition of rat liver FAS by Coomassie blue staining
Assay data:4 Active, 1 Activity ≤ 1 µM, 12 Tested
Inhibition of Sprague-Dawley rat liver fatty acid synthase at 60 umol
Inhibition of Sprague-Dawley rat liver fatty acid synthase
Assay data:3 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Decrease in fatty acid synthase activity in Wistar cafteria-fed rat epididymal adipose tissue at 70 mg/kg/day by DNA quantification assay
Decrease in fatty acid synthase activity in lean Wistar rat epididymal adipose tissue assessed at 70 mg/kg/day by DNA quantification assay
Decrease in fatty acid synthase activity in Wistar cafteria-fed rat inguinal adipose tissue at 70 mg/kg/day by DNA quantification assay
Decrease in fatty acid synthase activity in lean Wistar rat inguinal adipose tissue assessed at 70 mg/kg/day by DNA quantification assay
Inhibition of rat FAS
Assay data:14 Active, 10 Activity ≤ 1 µM, 23 Tested
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