BioAssay by Target (List) for Gene (Select 50488) - PubChem BioAssay - NCBI

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Select item 19608941.

Inhibition of MINK (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1960894

Summary PubMed Citation Related BioAssays by Target

Select item 19583732.

Inhibition of Mink1 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:3 Tested

AID:: 1958373

Summary PubMed Citation Related BioAssays by Target

Select item 19542193.

Inhibition of KCNQ1/MINK (unknown origin) at 10 uM

Source:: ChEMBL

Protein Targets:: Misshapen-like kinase 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1954219

Summary PubMed Citation Related BioAssays by Target

Select item 19282844.

Inhibition of MINK1 (unknown origin) at 25 nM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:6 Tested

AID:: 1928284

Summary PubMed Citation Related BioAssays by Target

Select item 19076095.

Inhibition of human MINK1 at 10 uM relative to control by Electrophysiological QPatch assay

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1907609

Summary PubMed Citation Related BioAssays by Target

Select item 18986796.

Inhibition of MINK1 (unknown origin) assessed as residual activity at 1 uM by radiometric 33 PanQuinase assay relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1898679

Summary PubMed Citation Related BioAssays by Target

Select item 18983237.

Inhibition of human MINK assessed as residual activity at 30 uM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1898323

Summary PubMed Citation Related BioAssays by Target

Select item 18890338.

Inhibition of MINK1 (unknown origin) at 1.0 uM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1889033

Summary PubMed Citation Related BioAssays by Target

Select item 18839549.

Inhibition of MINK1 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1883954

Summary PubMed Citation Related BioAssays by Target

Select item 188106310.

Inhibition of KCNQ1/MINK (unknown origin) by patch clamp method

Source:: ChEMBL

Protein Targets:: Misshapen-like kinase 1; ...
Total:: 2

Assay data:1 Tested

AID:: 1881063

Summary PubMed Citation Related BioAssays by Target

Select item 186043511.

Inhibition of MINK1 (unknown origin) at 0.5 uM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1860435

Summary PubMed Citation Related BioAssays by Target

Select item 183547612.

MINK DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1835476

Summary Related BioAssays by Target

Select item 183504413.

MINK(h) Kinase panel

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1835044

Summary Related BioAssays by Target

Select item 183421414.

Inhibition of MINK1 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1834214

Summary PubMed Citation Related BioAssays by Target

Select item 182347015.

Inhibition of MINK1 (unknown origin) at 1 uM by kinome scan method

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1823470

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 181330616.

Inhibition of MINK1 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Tested

AID:: 1813306

Summary PubMed Citation Related BioAssays by Target

Select item 180327417.

Kinase Assay from US Patent US9416123: "Kinase modulators for the treatment of cancer"

Source:: BindingDB

Protein Targets:: Activated CDC42 kinase 1; ...
Total:: 8

Assay data:12 Active, 7 Activity ≤ 1 µM, 16 Tested

AID:: 1803274

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 180045718.

Selectivity screening from Article 10.1038/nchembio.1629: "A unique inhibitor binding site in ER K1/2 is associated with slow binding kinetics"

Source:: BindingDB

Protein Targets:: Aurora kinase C; ...
Total:: 16

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1800457

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Depositor Related BioAssays by Target

Select item 179419719.

KinomeScan assay: inhibition of MINK

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:108 Tested

AID:: 1794197

Summary Related BioAssays by Target

Select item 179389120.

MINK [ZC3(MIN1LGF1)] Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Misshapen-like kinase 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793891

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (32)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (5)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (27)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (35)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (41)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (212)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (45)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (183)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (71)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 50488) (257)
PubChem BioAssay
misshapen-like kinase 1 isoform X24 [Homo sapiens]
misshapen-like kinase 1 isoform X24 [Homo sapiens]
gi|2462555689|ref|XP_054172303.1|

Protein
PREDICTED: Homo sapiens misshapen like kinase 1 (MINK1), transcript variant X11,...
PREDICTED: Homo sapiens misshapen like kinase 1 (MINK1), transcript variant X11, mRNA
gi|2462555662|ref|XM_054316315.1|

Nucleotide
misshapen-like kinase 1 isoform 4 [Homo sapiens]
misshapen-like kinase 1 isoform 4 [Homo sapiens]
gi|68161546|ref|NP_001020108.1|

Protein
RNA-directed DNA polymerase [Escherichia coli]
RNA-directed DNA polymerase [Escherichia coli]
gi|835778743|ref|WP_047657908.1|

Protein

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