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Agonist activity at NPRC in human Hela cells assessed as decrease in forskolin-induced cAMP level at 100 uM in presence of osteocrin
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at NPRC in human Hela cells assessed as decrease in forskolin-induced cAMP level at 100 uM in presence of M372049
Agonist activity at NPRC in human Hela cells assessed as decrease in forskolin-induced cAMP level at 100 uM relative to control
Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as maximum response by surface plasmon resonance analysis relative to control
Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analysis
Assay data:22 Tested
Agonist activity at NPRC in human HeLa cells assessed as decrease in forskolin-induced cAMP level at 100 nM in presence of M372049
Assay data:1 Tested
Agonist activity at NPRC in human HeLa cells assessed as decrease in forskolin-induced cAMP level at 100 nM in presence of osteocrin
Agonist activity at NPRC in human HeLa cells assessed as decrease in forskolin-induced cAMP level at 100 nM
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) at 300 uM by fluorescence polarization analysis relative to control
Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysis
Assay data:5 Tested
Atrial Natriuretic Factor (ANF) Eurofins-Panlabs radioligand binding assay
SummaryRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Displacement of [125I]-human ANP from His-tagged and Fc fragment containing human NPR-3 extracellular domain expressed in FreeStyle 293 cells incubated for 2 hrs by top count method
Assay data:26 Active, 16 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 26 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Human natriuretic peptide receptor 3 (Natriuretic peptide receptor family)
Assay data:6 Active, 6 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
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