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Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
SummaryPubMed Citation
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
In vitro inhibition of human Microsomal Triglyceride Transfer Protein (triglyceride transfer assay)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In vitro inhibition of human Microsomal Triglyceride Transfer Protein, (triglyceride transfer assay)
Assay data:6 Active, 3 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assay
Assay data:5 Active, 5 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
In vitro inhibition of human microsomal triglyceride transfer protein using triglyceride transfer assay
In vitro inhibitory activity against MTP using MTP transfer assay
Assay data:49 Active, 49 Activity ≤ 1 µM, 50 Tested
In vitro inhibition concentration required against triglyceride transfer of human Microsomal triglyceride transfer protein
In vitro inhibitory concentration against human Microsomal triglyceride transfer protein
Assay data:11 Active, 11 Activity ≤ 1 µM, 11 Tested
Inhibition of MTP in canine liver microsomes
Assay data:58 Active, 72 Activity ≤ 1 µM, 81 Tested
Inhibition of intestinal MTP in rat by murine gut retention assay
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MTP assessed as inhibition of apoB secretion from human HepG2 cells
Inhibition of MTP in human HepG2 cells assessed as apolipoprotein B production by ELISA
Assay data:10 Active, 2 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 10 Tested
Inhibition of microsomal triglyceride transfer protein by cell based assay
Assay data:2 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISA relative to dirlotapide
Assay data:13 Tested
Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISA
Assay data:19 Active, 19 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 19 Tested
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