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Assay for Inhibition of MMP from US Patent US20240050571: "CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE INHIBITORS AND AGENTS FOR BORON NEUTRON CAPTURE THERAPY"
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of MMP-9 (unknown origin) using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as fluorogenic substrate at 100 uM preincubated for 10 mins followed by substrate addition and measured for 25 mins by microplate reader assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MMP-9 (unknown origin) using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as fluorogenic substrate at 1 to 100 uM preincubated for 10 mins followed by substrate addition and measured for 25 mins by microplate reader assay
Inhibition of MMP-9 (unknown origin) using QXL520-gamma-Abu-Pro-Cha-Abu-Smc-His-Ala-Dab(5-FAM)-Ala-Lys-NH2 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured for 25 mins by microplate reader assay
Inhibition of MMP-9 (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorometric assay
Assay data:4 Tested
Inhibition of MMP-9 (unknown origin)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of beta-glucosidase activated MMP-9 (unknown origin) relative to control
Inhibition of human MMP-9 at 100 uM relative to control
Inhibition of human MMP-9
Assay data:5 Tested
Inhibition of MMP9 (unknown origin) assessed as inhibition constant
Assay data:8 Active, 8 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of MMP9 (unknown origin) assessed as dissociation constant
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of MMP9 (unknown origin)
Assay data:8 Active, 3 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 8 Tested
Assay data:5 Active, 5 Tested
Inhibition of MMP-9 (unknown origin) at 20 uM by fluorometric assay
Inhibition of human MMP9 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate preincubated for 0.5 hrs followed by substrate addition and measured after 6 hrs by fluorimeter analysis
Inhibition of recombinant human MMP9 using Dnp-Pro-Cha-Gly-Cys(ME)-His-Ala-Lys(Nma)-NH2 as substrate by fluorometer analysis
Inhibition of recombinant human MMP9 using Mca-Pro-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 20 to 30 mins by fluorescence microplate reader analysis
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of MMP-9 (unknown origin) using Ac-Pro-Leu-Gly-SCH(CH2 CH(CH3)2)CO-Leu-Gly-OCH2CH3 as substrate preincubated of 0.5 hrs followed by substrate addition and measured after 3 hrs by fluorescence analysis
Inhibition of MMP-9 (unknown origin) by fluorimetric assay
Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of recombinant human MMP9 using (7-methoxycoumarin-4-yl)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]-Ala-Arg-NH2 as substrate incubated for 0.5 hrs followed by substrate addition and measured for 16 hrs by fluorescence microplate reader analysis
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