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Inhibitory binding constant was determined against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II) from intercept of Michaelis-Menten plot
Assay data:6 Active, 5 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 2
Assay data:35 Active, 36 Activity ≤ 1 µM, 38 Tested
Inhibition of human inosine monophosphate dehydrogenase IMPDH II
Assay data:29 Active, 30 Activity ≤ 1 µM, 31 Tested
Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II
Assay data:34 Active, 34 Activity ≤ 1 µM, 34 Tested
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2
Assay data:29 Active, 29 Activity ≤ 1 µM, 30 Tested
Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzyme
Assay data:32 Active, 33 Activity ≤ 1 µM, 36 Tested
Inhibitory concentration against Inosine-5'-monophosphate dehydrogenase 2 was determined
Assay data:12 Active, 12 Activity ≤ 1 µM, 15 Tested
The compound was assayed to determine the inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2
Assay data:8 Active, 6 Activity ≤ 1 µM, 9 Tested
In vitro inhibition of Inosine-5'-monophosphate dehydrogenase 2.
Assay data:19 Active, 17 Activity ≤ 1 µM, 21 Tested
In vitro concentration that causes 50% inhibition of Inosine-5'-monophosphate dehydrogenase 2
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform); Range is 6-10 nM
Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Inhibitory activity against IMPDH II with respect to IMP and NAD
The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2
Assay data:4 Active, 3 Activity ≤ 1 µM, 5 Tested
The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2
Assay data:4 Active, 4 Activity ≤ 1 µM, 5 Tested
Inhibition of human inosine-5'-monophosphate dehydrogenase 2
Assay data:24 Active, 24 Activity ≤ 1 µM, 24 Tested
Inhibitory binding constant was determined against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II) from slope of Michaelis-Menten plot
Assay data:5 Active, 3 Activity ≤ 1 µM, 7 Tested
First order rate constant for inactivation of human Inosine-5'-monophosphate dehydrogenase 2
Assay data:3 Tested
Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II); NA is not active
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