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A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SNUC5)
Assay data:11 Active, 794 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (DIFI)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT115)
Assay data:14 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SW48)
Assay data:16 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HCC56)
Assay data:20 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (NCIH630)
Assay data:17 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (LS513)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SNUC1)
Assay data:9 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT29)
Assay data:15 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (RCM1)
Assay data:13 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT55)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (CAR1)
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HCT15)
Assay data:18 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (COLO678)
Assay data:22 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SW620)
Human isocitrate dehydrogenase (NADP(+)) 2, mitochondrial (1.1.1.42 Isocitrate dehydrogenases)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of IDH2 R140Q mutant (unknown origin) using alpha-ketoglutarate as substrate pretreated for 60 mins followed by substrate addition measured after 60 mins by resazurin dye based fluorescence assay
Assay data:2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of wild type IDH2/IDH2 R140Q mutant heterodimer (unknown origin) after 16 hrs in presence of NADPH by diaphorase/resazurin coupled fluorescence assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of wild type IDH2/IDH2 R172K mutant heterodimer (unknown origin) after 16 hrs in presence of NADPH by diaphorase/resazurin coupled fluorescence assay
Inhibition of IDH2 R140Q mutant homodimer (unknown origin) expressed in Sf9 cells pre-incubated for 1 hr before addition of alpha-KG followed by 16 hrs incubation in presence of NADPH, NADP, diaphorase and resazurin by fluorescence spectrometry based cofactor depletion assay
Assay data:251 Active, 256 Activity ≤ 1 µM, 256 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
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