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InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
SummaryPubMed Citation
Modulation of GFP-tagged survivin dimerization in HUVEC assessed as defect in mitotic progression at 50 to 100 nM after 48 hrs by real-time video microscopy relative to control
Assay data:1 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Modulation of GFP-tagged survivin dimerization in human PC3 cells assessed as defect in mitotic progression at 50 to 100 nM after 72 hrs by real-time video microscopy
Modulation of GFP-tagged survivin dimerization in HUVEC assessed as distorted, diffused or decondensed CPC organization at 10 nM after 48 hrs by real-time video microscopy relative to control
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Modulation of GFP-tagged survivin dimerization in HUVEC assessed as distorted, diffused or decondensed CPC organization at 50 to 100 nM after 48 hrs by real-time video microscopy relative to control
Assay data:2 Active, 2 Tested
Modulation of GFP-tagged survivin dimerization in human PC3 cells assessed as distorted, diffused or decondensed CPC organization at 50 to 100 nM after 72 hrs by real-time video microscopy relative to control
Modulation of GFP-tagged survivin dimerization in human PC3 cells assessed as distorted, diffused or decondensed CPC organization at 10 nM after 72 hrs by real-time video microscopy relative to control
Inhibition of survivin (unknown origin)
Assay data:1 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Modulation of GFP-tagged survivin dimerization in HUVEC assessed as reduction in cell number at 50 to 100 nM after 48 hrs by real-time video microscopy relative to control
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Activation of survivin in human Jurkat cells assessed as survivin phosphorylation at Thr32 residue at 0.1 uM after 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
Human baculoviral IAP repeat containing 5 (Inhibitors of apoptosis (IAP) protein family)
Induction of survivin degradation in human A375 cells after 24 hrs by Western blot analysis
Assay data:4 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Binding affinity to human survivin expressed in Escherichia coli BL21 cells after 30 mins
Assay data:29 Active, 20 Activity ≤ 1 µM, 32 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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