Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
ACC2 Enzyme Activity Assay from US Patent US11186587: "Compound as ACC inhibitor and use thereof"
Assay data:19 Active, 19 Activity ≤ 1 µM, 19 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
etermination of IC50 of Inhibition of Enzymatic Activity of ACC1 and ACC2 by the Compound of the Present Disclosure from US Patent US11142531: "Cyano substituted heteroarylpyrimidinone derivative, preparation method and use thereof"
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
In Vitro Acetyl-CoA Carboxylase (ACC) Inhibition Assay from US Patent US10995099: "Compounds and their uses as ACC inhibitors"
Assay data:52 Active, 6 Activity ≤ 1 nM, 59 Activity ≤ 1 µM, 59 Tested
Kinase Assay from US Patent US10759812: "Thienopyrimidine derivative and use thereof in medicine"
Assay data:15 Active, 6 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 15 Tested
Spectrophotometric 384 Well Assay from US Patent US9340510: "Tetrahydroisoquinoline derivatives, pharmaceutical compositions and uses thereof"
Assay data:245 Active, 244 Activity ≤ 1 µM, 245 Tested
Human ACC2 Enzyme Assay from US Patent US9278925: "Substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one"
Assay data:10 Active, 4 Activity ≤ 1 µM, 10 Tested
Spectrophotometric 384 Well Assay from US Patent US9278954: "Pyrrolidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:149 Active, 135 Activity ≤ 1 µM, 149 Tested
ACC2 Enzyme Assay A2 from US Patent US9212140: "(5s,8s)-3-(4′-chlor-3′-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5] dec-3-en-2-one (compound A) for treatment"
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
ACC2 Enzyme Assay B2 from US Patent US9212140: "(5s,8s)-3-(4′-chlor-3′-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5] dec-3-en-2-one (compound A) for treatment"
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Spectrophotometric 384 Well Assay from US Patent US9169205: "Pyrrolidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:197 Active, 186 Activity ≤ 1 µM, 197 Tested
Inhibition Assay from US Patent US8993586: "N1/N2-lactam acetyl-CoA carboxylase inhibitors"
Assay data:124 Active, 1 Activity ≤ 1 nM, 121 Activity ≤ 1 µM, 124 Tested
Spectrophotometric 384 Well Assay from US Patent US8962641: "Pyrimidine-substituted pyrrolidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:483 Active, 455 Activity ≤ 1 µM, 483 Tested
Spectrophotometric 384 Well Assay from US Patent US8877741: "Pyrrolidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:478 Active, 472 Activity ≤ 1 µM, 478 Tested
Spectrophotometric 384 Well Assay from US Patent US8835472: "Compounds, pharmaceutical compositions and uses thereof"
Assay data:611 Active, 384 Activity ≤ 1 µM, 663 Tested
Spectrophotometric 384 Well Assay from US Patent US8623860: "Azetidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:150 Active, 56 Activity ≤ 1 µM, 150 Tested
Enzyme Assay from US Patent US8530460: "Azetidine derivatives"
Assay data:195 Active, 112 Activity ≤ 1 µM, 199 Tested
Luminometric Assay from US Patent US8470841: "Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof"
Assay data:33 Active, 24 Activity ≤ 1 µM, 33 Tested
The Measurement of Inhibitory Activity on Human ACC1 and the ACC2 from US Patent US10233156: "9-membered fused ring derivative"
Assay data:57 Active, 57 Activity ≤ 1 µM, 57 Tested
In Vitro Acetyl-CoA Carboxylase (ACC) Inhibition Assay from US Patent US10208044: "ACC inhibitors and uses thereof"
Assay data:3 Tested
SummaryRelated BioAssays by Target
Inhibitory Activity on Human ACC1 and the ACC2 from US Patent US10150728: "Alkylene derivatives"
Assay data:701 Active, 688 Activity ≤ 1 µM, 701 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on