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Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
Activation of soluble guanylate cyclase (unknown origin) assessed as apparent initial rate of oxidation of oxyhemoglobin
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Activation of soluble guanylate cyclase (unknown origin) assessed as apparent initial rate of oxidation of oxyhemoglobin in presence of cysteine relative to GTN
Assay data:1 Tested
SummaryRelated BioAssays by Target
Activation of soluble guanylate cyclase (unknown origin) assessed as apparent initial rate of oxidation of oxyhemoglobin in presence of cysteine
Assay data:8 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Activation of human recombinant sGC subunit alpha-1/beta-1 using GTP as substrate assessed as cGMP production measured per ng of protein at 100 uM treated prior to DEA/NO addition measured after 2 mins by radioimmunoassay in presence of Mg2+ (Rvb = 2.21 +/- 0.15 pmol)
Assay data:11 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to sGC subunit alpha-1/beta-1 catalytic domain (unknown origin) assessed as occupancy relative to control
Binding affinity to full-length human recombinant sGC subunit alpha-1/beta-1 at 100 uM after 30 seconds by SPR analysis
Assay data:6 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to sGC subunit alpha-1/beta-1 catalytic domain (unknown origin) at 100 uM after 30 seconds by SPR analysis
Assay data:3 Tested
Binding affinity to sGC subunit alpha-1/beta-1 catalytic domain (unknown origin) at 100 uM after 30 seconds by SPR analysis in presence of GTP
Binding affinity to sGC subunit alpha-1/beta-1 catalytic domain (unknown origin) assessed as additive binding at 100 uM after 30 seconds by SPR analysis in presence of GTP
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Activation of human soluble guanylate cyclase assessed as production of cGMP in presence of nitric oxide donor, SIN-1 by FP assay
Assay data:10 Active, 9 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Activation of human soluble guanylate cyclase assessed as production of cGMP in presence of nitric oxide donor, SIN-1 by LC-MS enzyme assay
Assay data:16 Active, 11 Activity ≤ 1 µM, 16 Tested
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