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Inhibition of GSTM1-1 (unknown origin) at 100 uM using reduced GSH and CDNB as substrate incubated for 10 mins followed by substrate addition by microplate reader analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of GSTM1 in human A549 cells assessed as potentiation of cisplatin-induced cytotoxicity at 5 uM preincubated for 2 hrs followed by cisplatin addition measured after 48 hrs in presence of DTT by MTT assay
Inhibition of GSTM1 in human A549 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring combination index at 5 uM preincubated for 2 hrs followed by cisplatin addition measured after 48 hrs by MTT assay
Inhibition of GSTM1 in human A549 cells assessed as potentiation of cisplatin-induced cytotoxicity at 5 uM preincubated for 2 hrs followed by cisplatin addition measured after 48 hrs by MTT assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Noncompetitive inhibition of human GSTM1 using CDNB as substrate by Lineweaver-Burk plot analysis
Competitive inhibition of human GSTM1 using GSH as substrate by Lineweaver-Burk plot analysis
Inhibition of human GSTM1 using GSH as substrate after 3 mins by spectrophotometry
Assay data:24 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Counter screen to determine effect of SAR compounds for Rab7 project on GST-GSH binding, round 2
Assay data:12 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
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