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Binding affinity to GluK2 receptor (unknown origin)
Assay data:4 Active, 1 Activity ≤ 1 µM, 15 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Kainate CEREP ligand profiling
Assay data:1 Tested
SummaryRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Human GluK2 (Ionotropic glutamate receptors)
Assay data:7 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activity at ionotropic glutamate receptor 6 (unknown origin)
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [3H]-kainate from human recombinant GluK2 receptor expressed in HEK293 cell membranes after 60 mins
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Displacement of [3H]kianic acid from recombinant GluK2 kainate receptor (unknown origin) expressed in HEK293 cell membranes measured after 1 hr
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Antagonist activity at GluK2 (unknown origin) transfected in HEK293 cells assessed as inhibition of L-glutamate-induced peak current response at 1 mM compound added in background and L-glutamate solution by electrophysiological analysis relative to control
Agonist activity at GluK2 (unknown origin) transfected in HEK293 cells assessed as current responses at 1 mM by electrophysiological analysis
Assay data:2 Tested
Antagonist activity at GluK2 (unknown origin) transfected in HEK293 cells assessed as inhibition of L-glutamate-induced peak current responses at 1 mM compound added in background solution by electrophysiological analysis relative to control
Assay data:5 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Potentiation of recombinant homomeric GluK2 receptor (unknown origin) at 120 uM relative to control
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Displacement of [3H]-kainate from GluK2 receptor (unknown origin)
Assay data:4 Active, 1 Activity ≤ 1 µM, 4 Tested
Displacement of [3H]-kainate from GluK2 receptor (unknown origin) at 100 uM
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