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Binding affinity to GluK1 ligand binding domain (unknown origin)
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to GluK1 receptor (unknown origin)
Assay data:4 Active, 16 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Radioligand Binding Assay from US Patent US9656975: "Bicyclo[3.2.1]octyl amide derivatives and uses of same"
Assay data:10 Active, 1 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Displacement of [3H]kainate from human GluK1 expressed in HEK293 cell membranes after 60 mins by scintillation counting method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Human GluK1 (Ionotropic glutamate receptors)
Assay data:20 Active, 20 Tested
Displacement of [3H]kianic acid from recombinant GluK1 kainate receptor (unknown origin) expressed in HEK293 cell membranes measured after 1 hr
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Displacement of [3H]-kainate from GluK1 receptor (unknown origin)
Assay data:1 Active, 2 Tested
Displacement of [3H]-kainate from GluK1 receptor (unknown origin) at 100 uM
Assay data:4 Tested
Displacement of [3H]ATPA from human Gluk1 receptor
Assay data:27 Active, 15 Activity ≤ 1 µM, 31 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
Assay data:16 Active, 3 Activity ≤ 1 µM, 26 Tested
Inhibition of GluK1 receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at 3 uM by two-electrode voltage clamp method
Assay data:2 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
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