BioAssay by Target (List) for Gene (Select 2891) - PubChem BioAssay - NCBI

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Select item 4771201.

Agonist activity at recombinant GluA2 receptor flop isoform expressed in Xenopus oocytes

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:3 Active, 3 Tested

AID:: 477120

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 4772402.

Activity at recombinant GluA1A2 receptor flip isoform expressed in Xenopus oocytes assessed as effect on 300 uM glutamate-induced current

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 477240

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 4772383.

Activity at recombinant GluA1A2 receptor flop isoform expressed in Xenopus oocytes assessed as potentiation of glutamate-induced current at 100 uM relative to control

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:1 Tested

AID:: 477238

Summary PubMed Citation Related BioAssays by Target

Select item 4772374.

Activity at recombinant GluA1A2 receptor flip isoform expressed in Xenopus oocytes assessed as potentiation of glutamate-induced current at 100 uM relative to control

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:1 Tested

AID:: 477237

Summary PubMed Citation Related BioAssays by Target

Select item 4771535.

Antagonist activity at recombinant GluA1A2 receptor flip isoform expressed in Xenopus oocytes

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 477153

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4771486.

Antagonist activity at recombinant GluA1A2 receptor flip isoform expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 477148

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4771467.

Agonist activity at recombinant GluA1A2 receptor flip isoform expressed in Xenopus oocytes

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:2 Active, 3 Tested

AID:: 477146

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 4771428.

Agonist activity at recombinant GluA2 receptor flip isoform expressed in Xenopus oocytes

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 477142

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4771339.

Agonist activity at GluA2A3 receptor

Source:: ChEMBL

Protein Targets:: Glutamate receptor 2; ...
Total:: 2

Assay data:1 Tested

AID:: 477133

Summary PubMed Citation Related BioAssays by Target

Select item 47713210.

Agonist activity at GluA1A2 receptor

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:1 Tested

AID:: 477132

Summary PubMed Citation Related BioAssays by Target

Select item 47712811.

Agonist activity at GluA2 receptor

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:1 Active, 1 Tested

AID:: 477128

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 47712312.

Agonist activity at recombinant GluA2A3 receptor flop isoform expressed in Xenopus oocytes

Source:: ChEMBL

Protein Targets:: Glutamate receptor 2; ...
Total:: 2

Assay data:2 Tested

AID:: 477123

Summary PubMed Citation Related BioAssays by Target

Select item 47712213.

Agonist activity at recombinant GluA1A2 receptor flop isoform expressed in Xenopus oocytes

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:2 Tested

AID:: 477122

Summary PubMed Citation Related BioAssays by Target

Select item 47724114.

Activity at recombinant GluA1A2 receptor flop isoform expressed in Xenopus oocytes assessed as effect on 300 uM glutamate-induced current

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 2

Assay data:1 Tested

AID:: 477241

Summary PubMed Citation Related BioAssays by Target

Select item 36445515.

Inhibition of GluR2 receptor

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 364455

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 32060016.

Binding affinity at iGluR2o(R) receptor expressed in sf9 cells by radioligand binding assay

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 320600

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 32059817.

Binding affinity at iGluR2 receptor S1S2J domain expressed in sf9 cells by radioligand binding assay

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 320598

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 29734818.

Agonist activity at GluR2Q expressed in HEK293 cells relative to S-Glutamate by Fluo-4/Ca2+ assay

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:4 Tested

AID:: 297348

Summary PubMed Citation Related BioAssays by Target

Select item 29734719.

Agonist activity at GluR2Q expressed in HEK293 cells by Fluo-4/Ca2+ assay

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:6 Tested

AID:: 297347

Summary PubMed Citation Related BioAssays by Target

Select item 28112920.

Antagonist activity at human recombinant GLUA2-AMPA receptor expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx by FLIPR assay

Source:: ChEMBL

Protein Target:: Glutamate receptor 2

Assay data:1 Active, 5 Tested

AID:: 281129

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (100)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (57)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (110)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (10)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (179)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (14)
BioAssays reporting BioActivity of RNAi reagents

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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (179)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (13)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 2891) (193)
PubChem BioAssay
TCEAL8 transcription elongation factor A like 8 [Homo sapiens]
TCEAL8 transcription elongation factor A like 8 [Homo sapiens]
Gene ID:90843

Gene
Gene Links for GEO Profiles (Select 121500907) (1)
Gene

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