BioAssay by Target (List) for Gene (Select 2862) - PubChem BioAssay - NCBI

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Select item 5988061.

Agonist activity at motilin receptor

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 598806

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3715272.

Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by calcium mobilization-based FLIPR assay

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:9 Active, 7 Activity ≤ 1 µM, 9 Tested

AID:: 371527

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3715283.

Agonist activity at human recombinant motilin receptor expressed in CHO cells by calcium mobilization-based FLIPR assay

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:6 Active, 4 Activity ≤ 1 µM, 12 Tested

AID:: 371528

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3715294.

Intrinsic activity at human recombinant motilin receptor expressed in CHO cells by calcium mobilization-based FLIPR assay relative to motilin

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:6 Tested

AID:: 371529

Summary PubMed Citation Related BioAssays by Target

Select item 4119085.

Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assay

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:36 Active, 34 Activity ≤ 1 µM, 38 Tested

AID:: 411908

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4119136.

Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assay

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 411913

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4716967.

Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assay

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:40 Active, 28 Activity ≤ 1 µM, 49 Tested

AID:: 471696

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 4716978.

Intrinsic activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assay relative to motilin

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:40 Tested

AID:: 471697

Summary PubMed Citation Related BioAssays by Target

Select item 5107169.

Binding affinity to human recombinant motilin receptor

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:1 Tested

AID:: 510716

Summary PubMed Citation Related BioAssays by Target

Select item 52772910.

Agonist activity at motilin receptor

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 527729

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 34964611.

Binding affinity to motilin receptor

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:3 Active, 3 Tested

AID:: 349646

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 62409912.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 64667013.

Activity at human Mtl receptor at 10 uM

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:1 Tested

AID:: 646670

Summary PubMed Citation Related BioAssays by Target

Select item 65181014.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 65181115.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 68463516.

Inhibition of human motilin receptor at 5 uM by cell based assay

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:1 Tested

AID:: 684635

Summary PubMed Citation Related BioAssays by Target

Select item 71400017.

Inhibition of human Motilin receptor at 10 uM by CEREP assay

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:1 Tested

AID:: 714000

Summary PubMed Citation Related BioAssays by Target

Select item 72349518.

Antagonist activity at MLNR (unknown origin)

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 723495

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 72349719.

Agonist activity at MLNR (unknown origin)

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 723497

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 74241120.

SUPPLEMENTARY: Agonist activity at human recombinant motilin receptor expressed in CHO cells by calcium mobilization-based FLIPR assay. Same assay as CHEMBL942680

Source:: ChEMBL

Protein Target:: Motilin receptor

Assay data:71 Active, 10 Activity ≤ 1 nM, 71 Activity ≤ 1 µM, 71 Tested

AID:: 742411

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (26)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (6)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (23)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (25)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (64)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (46)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (30)
BioAssays deposited by other experimentalists

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