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In vitro inhibition of [11C]flumazenil binding to GABA-A central benzodiazepine receptor of rat brain
Assay data:6 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [3H]- muscimol from GABA-A receptor from rat cerebellum membrane at 0.022-0.039 uM
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Percent displacement of [3H]GABA at Gamma-aminobutyric acid receptor of rat brain membranes at 100 uM
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Percent displacement of [3H]GABA at Gamma-aminobutyric acid receptor of rat brain membranes at 0.01 uM
Assay data:2 Tested
Percent displacement of [3H]flunitrazepam from GABA-A receptor by 100 nM
Binding affinity to picrotoxin site of Gamma-aminobutyric acid receptor using [35S]TBPS as radioligand
Assay data:9 Tested
Displacement of [3H]- muscimol from GABA-A receptor from rat cerebellum membrane at 0.24-0.45 uM
Binding affinity to picrotoxin site of the Gamma-aminobutyric acid receptor was measured using [35S]TBPS as radioligand
Assay data:15 Tested
Displacement of [3H]diazepam from GABA-A receptor in rat synaptosomal membranes
Assay data:2 Active, 1 Activity ≤ 1 µM, 7 Tested
Inhibition of [3H]muscimol binding to Gamma-aminobutyric acid (GABA-A) receptor
Assay data:2 Activity ≤ 1 µM, 2 Tested
In vitro binding affinity at benzodiazepine receptor of rat cerebral cortical membranes by [3H]diazepam displacement.
Assay data:15 Active, 16 Activity ≤ 1 µM, 18 Tested
In vitro affinity at the Benzodiazepine receptor (BzR) is its ability to displace [3H]diazepam from BzR.
Assay data:10 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 15 Tested
In vitro displacement of [3H]flunitrazepam from GABA-A central benzodiazepine receptor of rat cerebral cortex membranes
Assay data:8 Active, 1 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested
Displacement of [3H]flunitrazepam (FNZ) from GABA-A benzodiazepine receptor in rat forebrain
Assay data:29 Active, 4 Activity ≤ 1 nM, 31 Activity ≤ 1 µM, 31 Tested
Inhibition of [3H]flunitrazepam binding to GABA-A benzodiazepine receptor of rat cortex
Inhibition of [3H]flunitrazepam binding to GABA-A benzodiazepine receptor of rat cerebellum
In vitro inhibition of [3H]THIP binding to Gamma-aminobutyric acid receptor in rat brain synaptic membranes
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Displacement of [3H]- muscimol from GABA-A receptor from rat cerebellum membrane at 0.003-0.006 uM
Inhibition of [3H]GABA binding to Gamma-aminobutyric acid receptor of rat brain synaptosomal membranes
Assay data:2 Active, 2 Activity ≤ 1 µM, 10 Tested
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