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Agonist activity at RXR-alpha in rat R3KE cells infected with oncogene KLF4-ER assessed as inhibition of KLF4-mediated oncogenic transformation
Assay data:6 Active, 7 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at RXRalpha in rat RK3E cells assessed as transcriptional activation by luciferase reporter gene assay
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
In vitro transcriptional activation in CV-1 cells expressing RXR-alpha; No activity
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RA
Assay data:17 Active, 2 Activity ≤ 1 nM, 17 Activity ≤ 1 µM, 17 Tested
In vitro evaluation against RXR-alpha in CV-1 cells by cotransfection assay was determined
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
In vitro transcriptional activation in CV-1 cells expressing RXR-alpha
Assay data:2 Active, 2 Activity ≤ 1 µM, 3 Tested
In vitro evaluation against RXR-alpha in CV-1 cells by cotransfection assay.
Assay data:14 Tested
Assay data:3 Tested
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
In vitro synergistic elevation of transcriptional activation in CV-1 cells expressing RAR and RXR with 3 nm TTNBP; No activity
In vitro synergistic elevation of transcriptional activation in CV-1 cells expressing RAR and RXR with 3 nm TTNBP
Assay data:17 Tested
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