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Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
Inhibition of FRbeta (unknown origin) expressed in Chinese hamster D4 cells assessed as cell growth inhibition incubated up to 96 hrs in presence of 200 nM folic acid by Celltiter-blue cell viability assay
Assay data:3 Active, 9 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of FRbeta (unknown origin) expressed in Chinese hamster D4 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-blue cell viability assay
Assay data:6 Active, 1 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Displacement of [3H]-folic acid from human folate receptor-beta expressed in Chinese hamster D4 cells after 15 mins
Assay data:5 Active, 6 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Inhibition of [3H]folic acid binding to FRbeta (unknown origin) expressed in Chinese hamster D4 cells
Assay data:7 Active, 8 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
Displacement of [3H]-folic acid from human FRbeta expressed in chinese hamster D4 cells after 15 mins
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [3H]folic acid from human FRbeta expressed in Chinese hamster D4 cells relative to unlabeled folic acid
Assay data:1 Active, 6 Tested
Displacement of [3H]folic acid from human FRbeta in Chinese hamster D4 cells
Assay data:4 Active, 4 Tested
Displacement of [3H]folic acid from human folate receptor beta in chinese hamster D4 cells assessed as relative binding affinity relative to folic acid
Assay data:8 Tested
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Displacement of [3H]folic acid from human FR-beta receptor expressed in Chinese hamster D4 cells measured after 15 mins
Assay data:3 Active, 4 Tested
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