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Binding affinity to recombinant human CBX6 by microarray based assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of CBX6 (unknown origin) assessed as inhibition of CBX4 disruption by competitive FP assay
Assay data:2 Active, 4 Tested
Binding affinity to CBX6 (unknown origin) assessed as dissociation constant by fluorescence polarization analysis
Assay data:8 Active, 7 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Binding affinity to human N-terminal his-tagged CBX6 chromodomain (8 to 65 residues) expressed in Escherichia coli Rosetta BL21(DE3)pLysS by ITC method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to 15N-labeled CBX6ChD (8 to 65 residues) (unknown origin) expressed in RIPL-BL21 (DE3)-CodonPlus competent cells at 200 uM by 1H-15N HSQC NMR spectroscopy
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to N-terminal His6-tagged human CBX6 (8 to 65 residues) expressed in Escherichia coli BL21 by surface plasmon resonance assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity to N-terminal His6-tagged human CBX6 (8 to 65 residues) expressed in Escherichia coli BL21 using FITC-peptide-3 as competitive binding probe by fluorescence polarization assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Assay data:478 Active, 1380 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Chromatin factor siRNA screen in epidermal stem cells
Assay data:97 Active, 331 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
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