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Activation of SIRT4 (unknown origin) at 10 uM using HMG-CPS1 as substrate
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to SIRT4 (unknown origin) assessed as increase in fluorescence intensity at 2.5 uM measured at 5 mins interval for 1 hr in presence of NAD+ by fluorometric method relative to control
Assay data:12 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Ratio of Kcat to Km at human N-terminal His6-tagged SIRT4 (25 to 314 residues) expressed in Escherichia coli codon plus (DE3)
Assay data:4 Tested
Activity at human N-terminal His6-tagged SIRT4 (25 to 314 residues) expressed in Escherichia coli codon plus (DE3)
Assay data:1 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Ratio of Kcat to Km at recombinant SIRT4 (unknown origin)
Assay data:6 Tested
Activity at recombinant SIRT4 (unknown origin) in presence of NAD by LC-MS analysis
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Assay data:478 Active, 1380 Tested
Activity of recombinant human SIRT4 assessed as deacylation of compound at 50 uM after 1 hr by trypsin developer-based fluorescence assay
Assay data:7 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Chromatin factor siRNA screen in epidermal stem cells
Assay data:97 Active, 331 Tested
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